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Black Cumin
Ingredient · 11 compounds · 9 conditions
Black Cumin is profiled across the CytoSolve® knowledge base and mapped to the disease biology it influences — tracing each of its compounds through disease, biological process, molecular pathway and down to individual biomarkers, with source videos and references at each step.
Compounds in this ingredient
⌬Carvacrol⌬Limonene⌬Magnesium⌬Thymol⌬Thymoquinone⌬Vitamin C⌬Vitamin E⌬p-Cymene⌬ß-sitosterol⌬β-Carotene⌬β-Sitosterol
Conditions addressed
❀Alzheimer's Disease❀Asthma❀Gut-Brain Health❀Metabolic Health❀Neurodegenerative Diseases❀Pain❀Skin Diseases❀Viral Infections❀Women's Health
Comparison
Ingredient → Compounds → Diseases → Biological Processes → Molecular Pathways → Biomarkers
All
Compound
Disease
Biological Process
Molecular Pathway
Compound · 5 disease(s) · 11 pathway(s)▸
Compound · 5 disease(s) · 11 pathway(s)
Disease · 3 process(es) · 3 pathway(s)▸
Disease · 3 process(es) · 3 pathway(s)
Disease · 1 process(es) · 4 pathway(s)▸
Disease · 1 process(es) · 4 pathway(s)
▸✣ Inflammation4 pathways
▸▣ NF-κB Signaling
◆COX-2, PGE2, 5-LOX
▸▣ Innate immune Signaling
◆IFN-γ
▸▣ TNF-α/ASK1/MAPK Signaling
◆ICAM-1, VCAM-1, Cad-11
▸▣ IL-1β Signaling
◆NO, PGE2, MMP-1, MMP-3, and MMP-13
Disease · 1 process(es) · 2 pathway(s)▸
Disease · 1 process(es) · 2 pathway(s)
▸✣ Inflammation2 pathways
▸▣ TPA-induced COX-2 Signaling
◆COX-2
▸▣ NLRP3 Signaling
◆IL-1β, IL-18
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Neurodegeneration1 pathway
▸▣ ROS Signaling
◆BCL-2, ROS
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ Inflammatory Signaling
◆Histamine/serotonin
Compound · 1 disease(s) · 1 pathway(s)▸
Compound · 1 disease(s) · 1 pathway(s)
Compound · 1 disease(s) · 2 pathway(s)▸
Compound · 1 disease(s) · 2 pathway(s)
Compound · 4 disease(s) · 4 pathway(s)▸
Compound · 4 disease(s) · 4 pathway(s)
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ NMDA Signaling
◆Substance P
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Energy Homeostasis1 pathway
▸▣ TCA Cycle Signaling
◆NADH
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Neuronal Hyperexcitability1 pathway
▸▣ NMDA Signaling
◆Intracellular Ca2+
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Neuronal Hyperexcitability1 pathway
▸▣ NMDA Signaling
◆Intracellular Ca2+ level
Compound · 3 disease(s) · 3 pathway(s)▸
Compound · 3 disease(s) · 3 pathway(s)
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ TH1/TH2/TH17 Signaling
◆IFN-γ, IL-13, IL-31 and IL-17A
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ LPS/TLR4 Signaling
◆TNF-α, IL-1IL-1β, and IL-6
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ LPS/TLR4 Signaling
◆TNF-α, IL-8
◆TNF-α, IL-1IL-1β, and IL-6
Compound · 4 disease(s) · 4 pathway(s)▸
Compound · 4 disease(s) · 4 pathway(s)
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ Dinitrofluorobenzene-induced Inflammatory Signaling
◆TSLP, IL-4, IL-6
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ LPS/TLR4 Signaling
◆TNF-α, IL-1, and IL-6
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Neurodegeneration1 pathway
▸▣ Cholesterol-induced Aβ Signaling
◆Aβ peptides
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ LPS/TLR4 Signaling
◆TNF-α, IL-8
Compound · 1 disease(s) · 1 pathway(s)▸
Compound · 1 disease(s) · 1 pathway(s)
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ LPS/TLR4 Signaling
◆TNF-α, IL-1β, and IL-6
Compound · 2 disease(s) · 3 pathway(s)▸
Compound · 2 disease(s) · 3 pathway(s)
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ LPS/TLR4 Signaling
◆TNF-α, IL-1, and IL-6
Disease · 2 process(es) · 2 pathway(s)▸
Disease · 2 process(es) · 2 pathway(s)
▸✣ Neuroplasticity1 pathway
▸▣ BDNF Signaling
◆BDNF
▸✣ Inflammation1 pathway
▸▣ Inflammatory Signaling
◆IL-2, IL-4 and INF-γ
Compound · 1 disease(s) · 1 pathway(s)▸
Compound · 1 disease(s) · 1 pathway(s)
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Depression1 pathway
▸▣ NMDA/cGMP Signaling
◆NO, cGMP
Compound · 2 disease(s) · 2 pathway(s)▸
Compound · 2 disease(s) · 2 pathway(s)
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Oxidative Stress1 pathway
▸▣ Oxidative Stress Pathway
◆MDA, Ox-GSH, NADPH Oxidase
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ TRPA1 Signaling
◆TNF-α, IL-1β, and KC
Compound · 1 disease(s) · 1 pathway(s)▸
Compound · 1 disease(s) · 1 pathway(s)
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ LPS Signaling
◆TNF-α, IL-1IL-1β, and IL-6