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Alzheimer's Disease
Disease / Phenomenon
A progressive neurodegenerative condition marked by the buildup of amyloid plaques and tau tangles in the brain, steadily eroding memory, reasoning, and everyday independence.
Biological Processes of Alzheimer's Disease
Explore the key biological processes that drive alzheimer's disease, from cellular mechanisms through tissue-level responses.
Oxidative Stress
3 pathway(s)
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Oxidative Stress
3 pathway(s)
Neurodegeneration
4 pathway(s)
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Neurodegeneration
4 pathway(s)
NeuroInflammation
8 pathway(s)
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NeuroInflammation
8 pathway(s)
Acetylcholine Signaling
Target: AchE
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Acetylcholine Signaling
Target: AchE
Aß aggregates
ROS Signaling
Target: Aß peptides
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ROS Signaling
Target: Aß peptides
Aß aggregates
M1 Polarization Signaling
Target: Choline Transporter-Like 1 (CTL1)
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M1 Polarization Signaling
Target: Choline Transporter-Like 1 (CTL1)
TNF-α
Amyloidogenic pathway
Target: Aß aggregation
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Amyloidogenic pathway
Target: Aß aggregation
Aß aggregates
Inflammation
2 pathway(s)
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Inflammation
2 pathway(s)
LPS/TLR4 Signaling
Target: NF-κB
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LPS/TLR4 Signaling
Target: NF-κB
TNF-α
IL-1IL-1β
and IL-6
LPS Signaling
Target: NF-κB
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LPS Signaling
Target: NF-κB
TNF-α
IL-1IL-1β
and IL-6
Compounds affecting Alzheimer's Disease
Browse active compounds and their direct impact on alzheimer's disease biological processes, pathways, and biomarkers.
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From Black Cumin
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From Black Cumin
Oxidative Stress
Oxidative Stress Pathway
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Oxidative Stress
Oxidative Stress Pathway
MDA
Ox-GSH
NADPH Oxidase
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From Ginseng
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From Ginseng
From Licorice
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From Licorice
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From Licorice
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From Licorice
NeuroInflammation
Amyloidogenic pathway
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NeuroInflammation
Amyloidogenic pathway
Aß aggregates
From Licorice
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From Licorice
NeuroInflammation
M1 Polarization Signaling
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NeuroInflammation
M1 Polarization Signaling
TNF-α
From Black Pepper
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From Black Pepper
From Black Cumin
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From Black Cumin
Inflammation
LPS/TLR4 Signaling
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Inflammation
LPS/TLR4 Signaling
TNF-α
IL-1IL-1β
and IL-6
From Ashwagandha
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From Ashwagandha
From Black Cumin
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From Black Cumin
Inflammation
LPS Signaling
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Inflammation
LPS Signaling
TNF-α
IL-1IL-1β
and IL-6
Ingredients affecting Alzheimer's Disease
Explore therapeutic ingredients and their constituent compounds that modulate alzheimer's disease biology.
1 active compound(s)
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1 active compound(s)
NeuroInflammation → TLR4 Signaling
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NeuroInflammation → TLR4 Signaling
3 active compound(s)
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3 active compound(s)
Oxidative Stress → Oxidative Stress Pathway
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Oxidative Stress → Oxidative Stress Pathway
MDA
Ox-GSH
NADPH Oxidase
Inflammation → LPS/TLR4 Signaling
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Inflammation → LPS/TLR4 Signaling
TNF-α
IL-1IL-1β
and IL-6
Inflammation → LPS Signaling
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Inflammation → LPS Signaling
TNF-α
IL-1IL-1β
and IL-6
1 active compound(s)
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1 active compound(s)
1 active compound(s)
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1 active compound(s)
NeuroInflammation → NF-κB Signaling
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NeuroInflammation → NF-κB Signaling
0 active compound(s)
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0 active compound(s)
1 active compound(s)
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1 active compound(s)
Neurodegeneration → Acetylcholine Signaling
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Neurodegeneration → Acetylcholine Signaling
1 active compound(s)
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1 active compound(s)
Neurodegeneration → Amyloidogenic pathway
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Neurodegeneration → Amyloidogenic pathway
Aß aggregates
3 active compound(s)
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3 active compound(s)
NeuroInflammation → HMGB-1/TLR4/NF-κB Signaling
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NeuroInflammation → HMGB-1/TLR4/NF-κB Signaling
NeuroInflammation → M1 Polarization Signaling
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NeuroInflammation → M1 Polarization Signaling
TNF-α
NeuroInflammation → Amyloidogenic pathway
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NeuroInflammation → Amyloidogenic pathway
Aß aggregates