ashwagandha - Gods

♧

Ashwagandha

Ingredient · 5 compounds · 4 conditions

Ashwagandha is profiled across the CytoSolve® knowledge base and mapped to the disease biology it influences — tracing each of its compounds through disease, biological process, molecular pathway and down to individual biomarkers, with source videos and references at each step.

Compounds in this ingredient

⌬Anatabine (trace)⌬Quercetin ⌬Withaferin A ⌬Withanolide A ⌬Withanone

Conditions addressed

❀Alzheimer's Disease ❀Gut-Brain Health ❀Inflammation ❀Osteoarthritis

Compare

Add ingredients to compare side-by-side

Ingredient → Compounds → Diseases → Biological Processes → Molecular Pathways → Biomarkers

All Compound Disease Biological Process Molecular Pathway

⌬

Compound · 3 disease(s) · 6 pathway(s)

▸

❀

Alzheimer's Disease

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ NeuroInflammation1 pathway

▸▣ TLR4 Signaling

◈ TargetNF-κB

◆IL-1β, IL-6, and TNF-α

▸✣ Oxidative Stress1 pathway

▸▣ Nrf2/ARE Signaling

◈ TargetNrf2

◆ROS, HO-1

❀

Disease · 1 process(es) · 2 pathway(s)

▸

▸✣ Inflammation2 pathways

▸▣ TNF-α/NF-κB Signaling

◈ TargetTNF-α

◆TNF-α and IL-1β

▶ Video ❀ Reference

▸▣ IL-6 Signaling

◈ TargetIL-6

◆IL-6, STAT3

▶ Video ❀ Reference

❀

Disease · 1 process(es) · 2 pathway(s)

▸

▸✣ Inflammation2 pathways

▸▣ NF-κB Signaling

◈ Targetp65

◆IL-1β, IL-10, TNF-α, COX-2, iNOS

▸▣ NF-κB/KPNA2/mIR1297 Signaling

◈ TargetP65

◆TNF-α, IL-17, mIR 1297, KPNA2

⌬

Compound · 2 disease(s) · 3 pathway(s)

▸

❀

Gut-Brain Health

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Neurotransmitter Imbalance1 pathway

▸▣ Neurotransmitter Signaling

◈ TargetSerotonin

◆Serotonin

▸✣ NeuroInflammation1 pathway

▸▣ Gut Microbiome-mediated NeuroInflammatory Signaling

◈ TargetIL-6, IL-17

◆IL-6, IL-17

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Cartilage Degeneration1 pathway

▸▣ Cathepsin B Signaling

◈ TargetCathepsin B

◆Cathepsin B

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ MAPK/NF-κB Signaling

◈ Targetp38 MAPK

◆TNF-α, IL-6

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ JAK1/STAT3/HIF-1α Signaling

◈ TargetJAK1

◆IL-1β, IL-6, IL-17, and TNF-α

⌬

Anatabine (trace)

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ NF-κB/STAT3 Signlaing

◈ Targetp-p65◈ Targetp-STAT

◆IL-6, IL-1β and TNF-α