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Piperine
Compound · in 2 ingredients · 6 conditions
Piperine is tracked across every ingredient that carries it and mapped to the disease biology it modulates, resolving down to molecular targets and biomarkers with linked evidence.
Found in these ingredients
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Compound → Diseases → Biological Processes → Pathways → Biomarkers
All
Disease
Biological Process
Molecular Pathway
❀Disease · 3 process(es) · 3 pathway(s)▸
Disease · 3 process(es) · 3 pathway(s)
▸✣ NeuroInflammation1 pathway
▸▣ LPS/TLR4 Signaling
▸✣ Oxidative Stress1 pathway
▸▣ Nrf2/ARE Signaling
▸✣ Neurodegeneration1 pathway
▸▣ Caspase-3 Signaling
❀Disease · 3 process(es) · 5 pathway(s)▸
Disease · 3 process(es) · 5 pathway(s)
▸✣ Inflammation3 pathways
▸▣ STAT6/GATA3/IL-4 Signaling
▸▣ Th2/Th17 Signaling
◈ TargetMast cell activation♧ IngredientBlack Pepper
◆IL-4, IL-6, IL-1β, IL-17A, and TNF-α
▸▣ IL1β Signaling
▸✣ Apoptosis1 pathway
▸▣ Oxidative Stress Signaling
◈ TargetMitochondrial complex III◈ TargetNADPH Oxidase◈ TargetXanthine Oxidase♧ IngredientLong Pepper
◆Cleaved PARP
▸✣ Cartilage Degeneration1 pathway
▸▣ IL1β Signaling
❀Disease · 2 process(es) · 3 pathway(s)▸
Disease · 2 process(es) · 3 pathway(s)
▸✣ Cholesterol Elimination2 pathways
▸▣ Cholesterol homeostasis Signaling
◈ TargetCholesterol 7α-hydroxylase (CYP7A1)♧ IngredientBlack Pepper
◆TG, LDL, Bile acid, Cholesterol
▸▣ LDL Signaling
◈ TargetLecithin-cholesterol acyltransferase (LCAT)♧ IngredientBlack Pepper
◆TG, LDL, Bile acid, Cholesterol
▸✣ Lipid Peroxidation1 pathway
▸▣ ROS Signaling
❀Disease · 4 process(es) · 4 pathway(s)▸
Disease · 4 process(es) · 4 pathway(s)
▸✣ Fat Digestion1 pathway
▸▣ Lipid Metabolic Signaling
▸✣ Carbohydrate Digestion1 pathway
▸▣ Carbohydrate Metabolic Signaling
◈ TargetSalivary and pancreatic α-amylase♧ IngredientBlack Pepper
◆Dietary Carbohydrate, monosaccharides, α-amylase
▸✣ Protein Digestion1 pathway
▸▣ Protein Metabolic Signaling
◈ TargetPepsin, Trypsin, Chymotrypsin♧ IngredientBlack Pepper
◆Dietary Protein, Pepsin, Trypsin, Chymotrypsin
▸✣ Inflammation1 pathway
▸▣ NF-κB Signaling
❀Disease · 2 process(es) · 2 pathway(s)▸
Disease · 2 process(es) · 2 pathway(s)
▸✣ Fibrosis1 pathway
▸▣ TGF-β/SMAD Signaling
▸✣ Inflammation1 pathway
▸▣ NF-κB Signaling
❀Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ IL-1β Signaling
◆MMP-3, MMP-13, iNOS and COX-2