Women's Health - Gods
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Women's Health

Disease / Phenomenon

Health concerns rooted in female physiology, including hormonal cycles, reproductive wellness, and related metabolic, bone, and inflammatory considerations.

Biological Processes of Women's Health

Explore the key biological processes that drive women's health, from cellular mechanisms through tissue-level responses.

Hormonal Imbalance
2 pathway(s)
ROS Signaling
Target: ROS
ROS
♧ Ingredient: Shatavari ⌬ Compound: Shatavarin-IV
Estradiol -17ß
♧ Ingredient: Shatavari ⌬ Compound: Shatavarin-IV
Estradiol/ER Signaling
Target: Estradiol
Estradiol
♧ Ingredient: Shatavari ⌬ Compound: Rutin
Apoptosis
12 pathway(s)
p53/Caspase-3 Signaling
Target: p53
Caspase-3
♧ Ingredient: Fenugreek ⌬ Compound: Diosgenin
p53
♧ Ingredient: Fenugreek ⌬ Compound: Diosgenin
NF-κB Signaling
Target: NF-κB
Caspase-3
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
Caspase-9
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
PARP
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
BCL-2
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
BAX
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
PI3K/AKT Signaling
Target: PTEN
PI3K
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
AKT
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
Cyclin D1
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
CDK4
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
CDK6
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
ROS Signaling
Target: ROS
SOD-1
♧ Ingredient: Inknut ⌬ Compound: Corilagin
PARG/PAR Signaling
Target: PAR
Caspase-3
♧ Ingredient: Inknut ⌬ Compound: Tannic Acid
MAPK1 Signaling
Target: MAPK1
NF-κB
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
PI3K/AKT/mTOR Signaling
Target: PI3K
ROS
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Protocatechuic acid
Caspase7/3 Signaling
Target: Caspase-9
Caspase-3
♧ Ingredient: Gall Nut ⌬ Compound: Tannic Acid
Caspase-3/8/9 Signaling
Target: Caspase-9
BAX and Bad
♧ Ingredient: Gall Nut ⌬ Compound: Syringic Acid
Caspase-3 Signaling
Target: BAX
BAX
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Bergenin
BCL-2
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Bergenin
Caspase-3
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Bergenin
p53 Signaling
Target: TP53
BAX
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Psoralen
p53
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Psoralen
p21
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Psoralen
Caspase3 Signaling
Target: ROS
BCL-2
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Umbelliferone
Lactogenesis Dysregulation
1 pathway(s)
Oxytocin Signaling
Target: Oxytocin
Oxytocin
♧ Ingredient: Fenugreek ⌬ Compound: Diosgenin
Oxidative Stress
3 pathway(s)
ROS Signaling
Target: ROS
ROS
♧ Ingredient: Black Cohosh ⌬ Compound: Actein
Nrf2/ARE Signaling
Target: Nrf2
CAT
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
SOD
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
GPX
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
Nrf2 Signaling
Target: AKT1
HO-1
♧ Ingredient: Betel Nut ⌬ Compound: Epicatechin
NQO-1
♧ Ingredient: Betel Nut ⌬ Compound: Epicatechin
SOD
♧ Ingredient: Betel Nut ⌬ Compound: Epicatechin
Inflammation
9 pathway(s)
MAPK/p38 Signaling
Target: MAPK/p38
TNF-α
♧ Ingredient: Black Cohosh ⌬ Compound: Actein
IL-6
♧ Ingredient: Black Cohosh ⌬ Compound: Actein
IL-1β
♧ Ingredient: Black Cohosh ⌬ Compound: Actein
NF-κB Signaling
Target: p-p65
TNF-α
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Epigallocatechin
IL-6
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Epigallocatechin
IL-1β
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Epigallocatechin
JNK Signaling
Target: JNK
TNF-α/TNFR Signaling
Target: NF-κB
TNF-α
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
IL-6
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
IL-1β
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
NF-κB/MAPK Signaling
Target: NF-κB
TNF-α
♧ Ingredient: Black Cumin - Seed ⌬ Compound: p-Cymene
IL-1β
♧ Ingredient: Black Cumin - Seed ⌬ Compound: p-Cymene
and IL-6
♧ Ingredient: Black Cumin - Seed ⌬ Compound: p-Cymene
LPS Signaling
Target: NF-κB
IL-1β
♧ Ingredient: Black Cumin - Seed ⌬ Compound: β-Sitosterol
TNF-α
♧ Ingredient: Black Cumin - Seed ⌬ Compound: β-Sitosterol
MAPK Signaling
Target: p38 MAPK
IL-1β
♧ Ingredient: Inknut ⌬ Compound: Chebulagic Acid
NF-κB/TNF-α Signaling
Target: NF-κB
NF-κB
♧ Ingredient: Fig Tree - Bark ⌬ Compound: β-Sitosterol
TNF-α
♧ Ingredient: Fig Tree - Bark ⌬ Compound: β-Sitosterol
PI3K/AKT Signaling
Target: p-PI3K
CD86
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Gallic Acid
Epithelial-Mesenchymal Transition
3 pathway(s)
ERK/HIF-1α Signaling
Target: ERK1/2
E-cadherin
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
N-cadherin
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
Vimentin
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
Wnt/β-catenin Signaling
Target: β-catenin
Cyclin D1
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Taxifolin
WIF1
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Taxifolin
β-catenin
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Taxifolin
JAK1/2/STAT3 Signaling
Target: JAK1/2
Vimentin
♧ Ingredient: Black Cumin - Seed ⌬ Compound: α-Hederin
N-cadherin
♧ Ingredient: Black Cumin - Seed ⌬ Compound: α-Hederin
Cell Proliferation
10 pathway(s)
BDNF/TrkB Signaling
Target: BDNF
BDNF
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
EGFR Signaling
Target: GSK-3β
AKT
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
GSK3β
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
and HER2
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
PI3K/AKT Signaling
Target: AKT
BCL-2 and BCL-xL
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
PI3K Signaling
Target: PIK3R1
PI3K
♧ Ingredient: Inknut ⌬ Compound: Ellagic Acid
GPCR/cAMP Signaling
Target: M2R
cAMP
♧ Ingredient: Betel Nut ⌬ Compound: Arecaidine
c-JUN Signaling
Target: c-JUN
E-cadherin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Interferon-γ Signaling
Target: Interferon-γ
E-cadherin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
MMP-9 Signaling
Target: MMP-9
E-cadherin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
CXCL Signaling
Target: CXCL
E-cadherin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
MAPK Signaling
Target: PDGFRB
PDGFRB
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Quercetin
RAS
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Quercetin
RAF
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Quercetin
Hyperandrogenism
1 pathway(s)
Hormone-induced Hyperandrogenism Signaling
Target: Progesterone and FSH
FSH
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
Progesterone
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
Testosterone
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
LH
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
Estradiol
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
Osteoblast Differentiation
1 pathway(s)
PTH Signaling
Target: Parathyroid hormone (PTH)
PTH
♧ Ingredient: Sesame Seed ⌬ Compound: Sesamol
BMP-2
♧ Ingredient: Sesame Seed ⌬ Compound: Sesamol
Ovarian Steroidogenesis
1 pathway(s)
CYP17A1/CYP19A1 Modulation
Target: CYP19A1
E1/E2 ratio
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
AS
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
TT
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
Milk Production
1 pathway(s)
HIF-1α/mTOR Signaling
Target: HIF-1α
HIF-1α
♧ Ingredient: Black Cumin - Seed ⌬ Compound: β-Sitosterol
Angiogenesis
8 pathway(s)
PTEN Signalling
Target: PTEN
PTEN
♧ Ingredient: Inknut ⌬ Compound: Gallic Acid
AKT Signaling
Target: AKT
AKT
♧ Ingredient: Inknut ⌬ Compound: Gallic Acid
HIF-1α Signaling
Target: HIF-1α
HIF-1α
♧ Ingredient: Inknut ⌬ Compound: Gallic Acid
VEGF Signaling
Target: VEGF
VEGF
♧ Ingredient: Inknut ⌬ Compound: Gallic Acid
VEGF-C/VEGFR2 Signaling
Target: VEGF-A
VEGF-A
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
VEGF-C/VEGFR3 Signaling
Target: VEGF-C
VEGF-C
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
VEGF-C/VEGFR4 Signaling
Target: VEGFR2
VEGFR2
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Wnt Signaling
Target: β-catenin
MMP-2
♧ Ingredient: Gall Nut ⌬ Compound: Syringic Acid
MMP-7
♧ Ingredient: Gall Nut ⌬ Compound: Syringic Acid
MMP-9
♧ Ingredient: Gall Nut ⌬ Compound: Syringic Acid
Fibrosis
2 pathway(s)
TGF-β1 Signaling
Target: TGF-β1
αSMA
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
Type I Collagen
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
CTGF
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
and FN
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
MAPK Signaling
Target: TGF-β1
Collagen-I
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Fibronectin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Pyroptosis
1 pathway(s)
NLRP3 Signaling
Target: NF-κB
IL-1β
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Epicatechin
Steroidogenesis
1 pathway(s)
AdipoR1 Signaling
Target: Adipo R1
Adiponectin
♧ Ingredient: Gall Nut ⌬ Compound: Gallic Acid
Serum Estrogen
♧ Ingredient: Gall Nut ⌬ Compound: Gallic Acid
Hormonal Regualtion
1 pathway(s)
GnRH Signaling
Target: DNA TOP3A
TOP 3
♧ Ingredient: Gall Nut ⌬ Compound: Ellagic Acid
Osteoclastogenesis
1 pathway(s)
RANKL Signaling
Target: p-AKT
F-Actin
♧ Ingredient: Gall Nut ⌬ Compound: Methyl Gallate
Immunomodulation
1 pathway(s)
IGSF3/TNFR2/NF-κB Signaling
Target: IGSF3
CD45+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
CD3e+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
CD4+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
CD25+ and FOXP3+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
Tissue Remodelling
1 pathway(s)
p38 MAPK Signaling
Target: p38 MAPK
MMP
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Acacetin
Hypercholesteremia
1 pathway(s)
AMPK Signaling
Target: AMPK
LDL
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Robinetinidol

Compounds affecting Women's Health

Browse active compounds and their direct impact on women's health biological processes, pathways, and biomarkers.

Inflammation
JNK Signaling
Tissue Remodelling
p38 MAPK Signaling
MMP
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Acacetin
Oxidative Stress
ROS Signaling
ROS
♧ Ingredient: Black Cohosh ⌬ Compound: Actein
Inflammation
MAPK/p38 Signaling
TNF-α
♧ Ingredient: Black Cohosh ⌬ Compound: Actein
IL-6
♧ Ingredient: Black Cohosh ⌬ Compound: Actein
IL-1β
♧ Ingredient: Black Cohosh ⌬ Compound: Actein
Cell Proliferation
GPCR/cAMP Signaling
cAMP
♧ Ingredient: Betel Nut ⌬ Compound: Arecaidine
Apoptosis
PI3K/AKT Signaling
PI3K
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
AKT
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
Cyclin D1
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
CDK4
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
CDK6
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
Apoptosis
Caspase-3 Signaling
BAX
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Bergenin
BCL-2
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Bergenin
Caspase-3
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Bergenin
Apoptosis
MAPK1 Signaling
NF-κB
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Cell Proliferation
c-JUN Signaling
E-cadherin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Cell Proliferation
Interferon-γ Signaling
E-cadherin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Cell Proliferation
MMP-9 Signaling
E-cadherin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Cell Proliferation
CXCL Signaling
E-cadherin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Angiogenesis
VEGF-C/VEGFR2 Signaling
VEGF-A
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Angiogenesis
VEGF-C/VEGFR3 Signaling
VEGF-C
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Angiogenesis
VEGF-C/VEGFR4 Signaling
VEGFR2
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Fibrosis
MAPK Signaling
Collagen-I
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Fibronectin
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Inflammation
MAPK Signaling
IL-1β
♧ Ingredient: Inknut ⌬ Compound: Chebulagic Acid
Oxidative Stress
Nrf2/ARE Signaling
CAT
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
SOD
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
GPX
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
Cell Proliferation
BDNF/TrkB Signaling
BDNF
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
Apoptosis
ROS Signaling
SOD-1
♧ Ingredient: Inknut ⌬ Compound: Corilagin
Cell Proliferation
EGFR Signaling
AKT
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
GSK3β
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
and HER2
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
Hyperandrogenism
Hormone-induced Hyperandrogenism Signaling
FSH
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
Progesterone
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
Testosterone
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
LH
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
Estradiol
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
Apoptosis
p53/Caspase-3 Signaling
Caspase-3
♧ Ingredient: Fenugreek ⌬ Compound: Diosgenin
p53
♧ Ingredient: Fenugreek ⌬ Compound: Diosgenin
Lactogenesis Dysregulation
Oxytocin Signaling
Oxytocin
♧ Ingredient: Fenugreek ⌬ Compound: Diosgenin
Cell Proliferation
PI3K Signaling
PI3K
♧ Ingredient: Inknut ⌬ Compound: Ellagic Acid
Hormonal Regualtion
GnRH Signaling
TOP 3
♧ Ingredient: Gall Nut ⌬ Compound: Ellagic Acid
Oxidative Stress
Nrf2 Signaling
HO-1
♧ Ingredient: Betel Nut ⌬ Compound: Epicatechin
NQO-1
♧ Ingredient: Betel Nut ⌬ Compound: Epicatechin
SOD
♧ Ingredient: Betel Nut ⌬ Compound: Epicatechin
Pyroptosis
NLRP3 Signaling
IL-1β
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Epicatechin
Inflammation
NF-κB Signaling
TNF-α
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Epigallocatechin
IL-6
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Epigallocatechin
IL-1β
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Epigallocatechin
Fibrosis
TGF-β1 Signaling
αSMA
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
Type I Collagen
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
CTGF
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
and FN
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
Inflammation
PI3K/AKT Signaling
CD86
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Gallic Acid
Angiogenesis
PTEN Signalling
PTEN
♧ Ingredient: Inknut ⌬ Compound: Gallic Acid
Angiogenesis
AKT Signaling
AKT
♧ Ingredient: Inknut ⌬ Compound: Gallic Acid
Angiogenesis
HIF-1α Signaling
HIF-1α
♧ Ingredient: Inknut ⌬ Compound: Gallic Acid
Angiogenesis
VEGF Signaling
VEGF
♧ Ingredient: Inknut ⌬ Compound: Gallic Acid
Steroidogenesis
AdipoR1 Signaling
Adiponectin
♧ Ingredient: Gall Nut ⌬ Compound: Gallic Acid
Serum Estrogen
♧ Ingredient: Gall Nut ⌬ Compound: Gallic Acid
Osteoclastogenesis
RANKL Signaling
F-Actin
♧ Ingredient: Gall Nut ⌬ Compound: Methyl Gallate
Apoptosis
PI3K/AKT/mTOR Signaling
ROS
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Protocatechuic acid
Apoptosis
p53 Signaling
BAX
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Psoralen
p53
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Psoralen
p21
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Psoralen
Immunomodulation
IGSF3/TNFR2/NF-κB Signaling
CD45+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
CD3e+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
CD4+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
CD25+ and FOXP3+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
Cell Proliferation
MAPK Signaling
PDGFRB
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Quercetin
RAS
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Quercetin
RAF
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Quercetin
Hypercholesteremia
AMPK Signaling
LDL
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Robinetinidol
Hormonal Imbalance
Estradiol/ER Signaling
Estradiol
♧ Ingredient: Shatavari ⌬ Compound: Rutin
Osteoblast Differentiation
PTH Signaling
PTH
♧ Ingredient: Sesame Seed ⌬ Compound: Sesamol
BMP-2
♧ Ingredient: Sesame Seed ⌬ Compound: Sesamol
Hormonal Imbalance
ROS Signaling
ROS
♧ Ingredient: Shatavari ⌬ Compound: Shatavarin-IV
Estradiol -17ß
♧ Ingredient: Shatavari ⌬ Compound: Shatavarin-IV
Apoptosis
Caspase-3/8/9 Signaling
BAX and Bad
♧ Ingredient: Gall Nut ⌬ Compound: Syringic Acid
Angiogenesis
Wnt Signaling
MMP-2
♧ Ingredient: Gall Nut ⌬ Compound: Syringic Acid
MMP-7
♧ Ingredient: Gall Nut ⌬ Compound: Syringic Acid
MMP-9
♧ Ingredient: Gall Nut ⌬ Compound: Syringic Acid
Apoptosis
PARG/PAR Signaling
Caspase-3
♧ Ingredient: Inknut ⌬ Compound: Tannic Acid
Apoptosis
Caspase7/3 Signaling
Caspase-3
♧ Ingredient: Gall Nut ⌬ Compound: Tannic Acid
Epithelial-Mesenchymal Transition
Wnt/β-catenin Signaling
Cyclin D1
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Taxifolin
WIF1
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Taxifolin
β-catenin
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Taxifolin
Apoptosis
NF-κB Signaling
Caspase-3
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
Caspase-9
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
PARP
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
BCL-2
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
BAX
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
Inflammation
TNF-α/TNFR Signaling
TNF-α
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
IL-6
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
IL-1β
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
Epithelial-Mesenchymal Transition
ERK/HIF-1α Signaling
E-cadherin
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
N-cadherin
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
Vimentin
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
Cell Proliferation
PI3K/AKT Signaling
BCL-2 and BCL-xL
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
Ovarian Steroidogenesis
CYP17A1/CYP19A1 Modulation
E1/E2 ratio
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
AS
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
TT
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
Apoptosis
Caspase3 Signaling
BCL-2
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Umbelliferone
Inflammation
NF-κB/MAPK Signaling
TNF-α
♧ Ingredient: Black Cumin - Seed ⌬ Compound: p-Cymene
IL-1β
♧ Ingredient: Black Cumin - Seed ⌬ Compound: p-Cymene
and IL-6
♧ Ingredient: Black Cumin - Seed ⌬ Compound: p-Cymene
Epithelial-Mesenchymal Transition
JAK1/2/STAT3 Signaling
Vimentin
♧ Ingredient: Black Cumin - Seed ⌬ Compound: α-Hederin
N-cadherin
♧ Ingredient: Black Cumin - Seed ⌬ Compound: α-Hederin
Inflammation
LPS Signaling
IL-1β
♧ Ingredient: Black Cumin - Seed ⌬ Compound: β-Sitosterol
TNF-α
♧ Ingredient: Black Cumin - Seed ⌬ Compound: β-Sitosterol
Inflammation
NF-κB/TNF-α Signaling
NF-κB
♧ Ingredient: Fig Tree - Bark ⌬ Compound: β-Sitosterol
TNF-α
♧ Ingredient: Fig Tree - Bark ⌬ Compound: β-Sitosterol
Milk Production
HIF-1α/mTOR Signaling
HIF-1α
♧ Ingredient: Black Cumin - Seed ⌬ Compound: β-Sitosterol

Ingredients affecting Women's Health

Explore therapeutic ingredients and their constituent compounds that modulate women's health biology.

5 active compound(s)
Apoptosis → PI3K/AKT Signaling
PI3K
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
AKT
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
Cyclin D1
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
CDK4
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
CDK6
♧ Ingredient: Betel Nut ⌬ Compound: Arecoline
Apoptosis → MAPK1 Signaling
NF-κB
♧ Ingredient: Betel Nut ⌬ Compound: Catechin
Oxidative Stress → Nrf2 Signaling
HO-1
♧ Ingredient: Betel Nut ⌬ Compound: Epicatechin
NQO-1
♧ Ingredient: Betel Nut ⌬ Compound: Epicatechin
SOD
♧ Ingredient: Betel Nut ⌬ Compound: Epicatechin
Cell Proliferation → GPCR/cAMP Signaling
cAMP
♧ Ingredient: Betel Nut ⌬ Compound: Arecaidine
Fibrosis → TGF-β1 Signaling
αSMA
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
Type I Collagen
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
CTGF
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
and FN
♧ Ingredient: Betel Nut ⌬ Compound: Epigallocatechin-3-gallate
4 active compound(s)
Apoptosis → PI3K/AKT/mTOR Signaling
ROS
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Protocatechuic acid
Epithelial-Mesenchymal Transition → Wnt/β-catenin Signaling
Cyclin D1
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Taxifolin
WIF1
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Taxifolin
β-catenin
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Taxifolin
Cell Proliferation → MAPK Signaling
PDGFRB
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Quercetin
RAS
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Quercetin
RAF
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Quercetin
Pyroptosis → NLRP3 Signaling
IL-1β
♧ Ingredient: Black Catechu - Resin ⌬ Compound: Epicatechin
2 active compound(s)
Oxidative Stress → ROS Signaling
ROS
♧ Ingredient: Black Cohosh ⌬ Compound: Actein
Inflammation → JNK Signaling
1 active compound(s)
Inflammation → TNF-α/TNFR Signaling
TNF-α
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
IL-6
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
IL-1β
♧ Ingredient: Black Cumin ⌬ Compound: Thymoquinone
4 active compound(s)
Apoptosis → NF-κB Signaling
Caspase-3
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
Caspase-9
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
PARP
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
BCL-2
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
BAX
♧ Ingredient: Black Cumin - Seed ⌬ Compound: Thymoquinone
Inflammation → NF-κB/MAPK Signaling
TNF-α
♧ Ingredient: Black Cumin - Seed ⌬ Compound: p-Cymene
IL-1β
♧ Ingredient: Black Cumin - Seed ⌬ Compound: p-Cymene
and IL-6
♧ Ingredient: Black Cumin - Seed ⌬ Compound: p-Cymene
Inflammation → LPS Signaling
IL-1β
♧ Ingredient: Black Cumin - Seed ⌬ Compound: β-Sitosterol
TNF-α
♧ Ingredient: Black Cumin - Seed ⌬ Compound: β-Sitosterol
Epithelial-Mesenchymal Transition → JAK1/2/STAT3 Signaling
Vimentin
♧ Ingredient: Black Cumin - Seed ⌬ Compound: α-Hederin
N-cadherin
♧ Ingredient: Black Cumin - Seed ⌬ Compound: α-Hederin
1 active compound(s)
Oxidative Stress → Nrf2/ARE Signaling
CAT
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
SOD
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
GPX
♧ Ingredient: Cinnamon ⌬ Compound: Cinnamaldehyde
1 active compound(s)
Apoptosis → p53/Caspase-3 Signaling
Caspase-3
♧ Ingredient: Fenugreek ⌬ Compound: Diosgenin
p53
♧ Ingredient: Fenugreek ⌬ Compound: Diosgenin
3 active compound(s)
Apoptosis → Caspase-3 Signaling
BAX
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Bergenin
BCL-2
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Bergenin
Caspase-3
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Bergenin
Apoptosis → p53 Signaling
BAX
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Psoralen
p53
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Psoralen
p21
♧ Ingredient: Fig Tree - Bark ⌬ Compound: Psoralen
Inflammation → NF-κB/TNF-α Signaling
NF-κB
♧ Ingredient: Fig Tree - Bark ⌬ Compound: β-Sitosterol
TNF-α
♧ Ingredient: Fig Tree - Bark ⌬ Compound: β-Sitosterol
6 active compound(s)
Apoptosis → Caspase7/3 Signaling
Caspase-3
♧ Ingredient: Gall Nut ⌬ Compound: Tannic Acid
Apoptosis → Caspase-3/8/9 Signaling
BAX and Bad
♧ Ingredient: Gall Nut ⌬ Compound: Syringic Acid
Steroidogenesis → AdipoR1 Signaling
Adiponectin
♧ Ingredient: Gall Nut ⌬ Compound: Gallic Acid
Serum Estrogen
♧ Ingredient: Gall Nut ⌬ Compound: Gallic Acid
Hormonal Regualtion → GnRH Signaling
TOP 3
♧ Ingredient: Gall Nut ⌬ Compound: Ellagic Acid
Osteoclastogenesis → RANKL Signaling
F-Actin
♧ Ingredient: Gall Nut ⌬ Compound: Methyl Gallate
Immunomodulation → IGSF3/TNFR2/NF-κB Signaling
CD45+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
CD3e+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
CD4+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
CD25+ and FOXP3+
♧ Ingredient: Gall Nut ⌬ Compound: Purpurogallin
5 active compound(s)
Apoptosis → Caspase3 Signaling
BCL-2
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Umbelliferone
Inflammation → NF-κB Signaling
TNF-α
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Epigallocatechin
IL-6
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Epigallocatechin
IL-1β
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Epigallocatechin
Inflammation → PI3K/AKT Signaling
CD86
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Gallic Acid
Tissue Remodelling → p38 MAPK Signaling
MMP
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Acacetin
Hypercholesteremia → AMPK Signaling
LDL
♧ Ingredient: Gum Arabic Tree - Bark ⌬ Compound: Robinetinidol
5 active compound(s)
Apoptosis → ROS Signaling
SOD-1
♧ Ingredient: Inknut ⌬ Compound: Corilagin
Apoptosis → PARG/PAR Signaling
Caspase-3
♧ Ingredient: Inknut ⌬ Compound: Tannic Acid
Inflammation → MAPK Signaling
IL-1β
♧ Ingredient: Inknut ⌬ Compound: Chebulagic Acid
Cell Proliferation → PI3K Signaling
PI3K
♧ Ingredient: Inknut ⌬ Compound: Ellagic Acid
Angiogenesis → PTEN Signalling
PTEN
♧ Ingredient: Inknut ⌬ Compound: Gallic Acid
1 active compound(s)
Osteoblast Differentiation → PTH Signaling
PTH
♧ Ingredient: Sesame Seed ⌬ Compound: Sesamol
BMP-2
♧ Ingredient: Sesame Seed ⌬ Compound: Sesamol
2 active compound(s)
Hormonal Imbalance → ROS Signaling
ROS
♧ Ingredient: Shatavari ⌬ Compound: Shatavarin-IV
Estradiol -17ß
♧ Ingredient: Shatavari ⌬ Compound: Shatavarin-IV
Hormonal Imbalance → Estradiol/ER Signaling
Estradiol
♧ Ingredient: Shatavari ⌬ Compound: Rutin
1 active compound(s)
Cell Proliferation → EGFR Signaling
AKT
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
GSK3β
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
and HER2
♧ Ingredient: Turmeric ⌬ Compound: Curcumin