betel-nut - Gods

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Betel Nut

Ingredient · 5 compounds · 1 conditions

Betel Nut is profiled across the CytoSolve® knowledge base and mapped to the disease biology it influences — tracing each of its compounds through disease, biological process, molecular pathway and down to individual biomarkers, with source videos and references at each step.

Compounds in this ingredient

⌬Arecaidine ⌬Arecoline ⌬Catechin ⌬Epicatechin ⌬Epigallocatechin-3-gallate

Conditions addressed

❀Women's Health

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Ingredient → Compounds → Diseases → Biological Processes → Molecular Pathways → Biomarkers

All Compound Disease Biological Process Molecular Pathway

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Apoptosis1 pathway

▸▣ PI3K/AKT Signaling

◈ TargetPTEN

◆Cytokeratin 18, PARP, Caspase 8, Caspase-9, Caspase-3, Caspase 7, BAX, Bad, Bik, Bid

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Cell Proliferation1 pathway

▸▣ GPCR/cAMP Signaling

◈ TargetM2R

◆cAMP

⌬

Epigallocatechin-3-gallate

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Fibrosis1 pathway

▸▣ TGF-β1 Signaling

◈ TargetTGF-β1

◆αSMA, Type I Collagen, CTGF, and FN

⌬

Compound · 1 disease(s) · 9 pathway(s)

▸

❀

Disease · 4 process(es) · 9 pathway(s)

▸

▸✣ Angiogenesis3 pathways

▸▣ VEGF-C/VEGFR2 Signaling

◈ TargetVEGF-A

◆VEGF-A

▸▣ VEGF-C/VEGFR3 Signaling

◈ TargetVEGF-C

◆VEGF-C

▸▣ VEGF-C/VEGFR4 Signaling

◈ TargetVEGFR2

◆VEGFR2

▸✣ Fibrosis1 pathway

▸▣ MAPK Signaling

◈ TargetTGF-β1

◆Collagen-I, Fibronectin

▸✣ Apoptosis1 pathway

▸▣ MAPK1 Signaling

◈ TargetNF-κB◈ TargetMAPK1

◆NF-κB

▸✣ Cell Proliferation4 pathways

▸▣ c-JUN Signaling

◈ Targetc-JUN

◆E-cadherin

▸▣ Interferon-γ Signaling

◈ TargetInterferon-γ

◆E-cadherin

▸▣ MMP-9 Signaling

◈ TargetMMP-9

◆E-cadherin

▸▣ CXCL Signaling

◈ TargetCXCL

◆E-cadherin

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Oxidative Stress1 pathway

▸▣ Nrf2 Signaling

◈ TargetAKT1

◆HO-1, NQO-1, SOD