Renal Diseases - Gods
← Back to Home

Renal Diseases

Disease / Phenomenon

Conditions that impair the kidneys' filtering and balancing roles, affecting waste clearance, fluid regulation, and mineral equilibrium.

Biological Processes of Renal Diseases

Explore the key biological processes that drive renal diseases, from cellular mechanisms through tissue-level responses.

Fibrosis
1 pathway(s)
TGF-β1 Signaling
Target: TGF-β1
Smad-3
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
Collagen
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
Inflammation
1 pathway(s)
TLR4/NF-κB Signaling
Target: NF-κB
IL-1β
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
IL-18
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
Mitochondrial Dysfunction
1 pathway(s)
ROS Signaling
Target: ROS
ROS
♧ Ingredient: Milk Thistle ⌬ Compound: Silymarin
ATP
♧ Ingredient: Milk Thistle ⌬ Compound: Silymarin
Lipid accumulation
♧ Ingredient: Milk Thistle ⌬ Compound: Silymarin
Apoptosis
1 pathway(s)
AKT/mTOR Signaling
Target: GLI-1
GLI-1
♧ Ingredient: Milk Thistle ⌬ Compound: Silibinin
BCL-2
♧ Ingredient: Milk Thistle ⌬ Compound: Silibinin

Compounds affecting Renal Diseases

Browse active compounds and their direct impact on renal diseases biological processes, pathways, and biomarkers.

Fibrosis
TGF-β1 Signaling
Smad-3
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
Collagen
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
Inflammation
TLR4/NF-κB Signaling
IL-1β
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
IL-18
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
Apoptosis
AKT/mTOR Signaling
GLI-1
♧ Ingredient: Milk Thistle ⌬ Compound: Silibinin
BCL-2
♧ Ingredient: Milk Thistle ⌬ Compound: Silibinin
Mitochondrial Dysfunction
ROS Signaling
ROS
♧ Ingredient: Milk Thistle ⌬ Compound: Silymarin
ATP
♧ Ingredient: Milk Thistle ⌬ Compound: Silymarin
Lipid accumulation
♧ Ingredient: Milk Thistle ⌬ Compound: Silymarin

Ingredients affecting Renal Diseases

Explore therapeutic ingredients and their constituent compounds that modulate renal diseases biology.

1 active compound(s)
Fibrosis → TGF-β1 Signaling
Smad-3
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
Collagen
♧ Ingredient: Blueberry ⌬ Compound: Pterostilbene
2 active compound(s)
Mitochondrial Dysfunction → ROS Signaling
ROS
♧ Ingredient: Milk Thistle ⌬ Compound: Silymarin
ATP
♧ Ingredient: Milk Thistle ⌬ Compound: Silymarin
Lipid accumulation
♧ Ingredient: Milk Thistle ⌬ Compound: Silymarin
Apoptosis → AKT/mTOR Signaling
GLI-1
♧ Ingredient: Milk Thistle ⌬ Compound: Silibinin
BCL-2
♧ Ingredient: Milk Thistle ⌬ Compound: Silibinin