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Neem
Ingredient · 6 compounds · 4 conditions

Neem is profiled across the CytoSolve® knowledge base and mapped to the disease biology it influences — tracing each of its compounds through disease, biological process, molecular pathway and down to individual biomarkers, with source videos and references at each step.

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Comparison

All Compound Disease Biological Process Molecular Pathway
Compound · 2 disease(s) · 4 pathway(s)
Disease · 2 process(es) · 3 pathway(s)
Apoptosis1 pathway
PI3K/AKT Signaling
◈ TargetPI3K
BAX/BCL-2 ratio, Caspase-9 and Caspase--3
Inflammation2 pathways
PI3K/AKT/GSK-3β signalling
◈ TargetPI3K
Porphyromonas gingivalis
ROS Signaling
◈ TargetROS
ROS
Disease · 1 process(es) · 1 pathway(s)
Inflammation1 pathway
NF-κB Signaling
◈ TargetNF-κB
COX-2, PGE2, 5-LOX, TNF-α, IL-6, IL-1β
Compound · 1 disease(s) · 1 pathway(s)
Disease · 1 process(es) · 1 pathway(s)
Angiogenesis1 pathway
VEGF Signaling
◈ TargetVEGF
VEGF
Compound · 1 disease(s) · 1 pathway(s)
Disease · 1 process(es) · 1 pathway(s)
Melanogenesis1 pathway
α-MSH/MC1R Signaling
◈ TargetTyrosinase
MITF, Tyrosinase
Compound · 2 disease(s) · 2 pathway(s)
Disease · 1 process(es) · 1 pathway(s)
Tissue Remodelling1 pathway
ROS/AP-1 Signaling
◈ TargetROS
ROS, MMP-1
Disease · 1 process(es) · 1 pathway(s)
Testosterone Degradation1 pathway
Testosterone Degradation Signaling
◈ Target5 alpha-reductase
5 alpha-reductase
Compound · 1 disease(s) · 1 pathway(s)
Disease · 1 process(es) · 1 pathway(s)
Inflammation1 pathway
NF-κB Signaling
◈ TargetNF-κB
COX-2, PGE2, 5-LOX, TNF-α, IL-6, IL-1β
Compound · 1 disease(s) · 1 pathway(s)
Disease · 1 process(es) · 1 pathway(s)
Inflammation1 pathway
NF-κB Signaling
◈ TargetNF-κB
COX-2, PGE2, 5-LOX, TNF-α, IL-6, IL-1β