dried-ginger - Gods

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Dried Ginger

Ingredient · 8 compounds · 3 conditions

Dried Ginger is profiled across the CytoSolve® knowledge base and mapped to the disease biology it influences — tracing each of its compounds through disease, biological process, molecular pathway and down to individual biomarkers, with source videos and references at each step.

Compounds in this ingredient

⌬10-Gingerol ⌬10-Shogaol ⌬6-Gingerol ⌬6-Paradol ⌬6-Shogaol ⌬8-Shogaol ⌬Gingerenone-A ⌬Zingerone

Conditions addressed

❀Asthma ❀Liver Health ❀Osteoarthritis

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Ingredient → Compounds → Diseases → Biological Processes → Molecular Pathways → Biomarkers

All Compound Disease Biological Process Molecular Pathway

⌬

Compound · 3 disease(s) · 4 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Oxidative Stress1 pathway

▸▣ JNK/Nrf2 Signaling

◈ TargetNrf2

◆HO-1, GCS, GSH

❀

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Apoptosis1 pathway

▸▣ EGFR Signaling

◈ TargetAKT

◆p-AKT, Cleaved Caspase-3

▸✣ Cell Cycle Progression1 pathway

▸▣ EGFR Signaling

◈ TargetAKT

◆p-AKT, Cyclin D1/3

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ PI3K/AKT/NF-κB Signaling

◈ TargetPPAR-γ

◆TNF-α, IL-1β, IL-6, IL-8, MMP-2, and MP-9

⌬

Compound · 3 disease(s) · 4 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Oxidative Stress1 pathway

▸▣ LKB1/AMPK Signaling

◈ TargetLKB1

◆GPx, CAT, ROS

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Fibrosis1 pathway

▸▣ TGF-β1 Signaling

◈ TargetSIRT1

◆α-SMA, Collagen IV

❀

Disease · 1 process(es) · 2 pathway(s)

▸

▸✣ Inflammation2 pathways

▸▣ IL-1/RANKL Signaling

◈ TargetRANKL

◆PGE2

▸▣ NF-κB Signaling

◈ TargetmiR-30c-2-3p/TAB1

◆TNF-α, IL-6

⌬

Compound · 3 disease(s) · 5 pathway(s)

▸

❀

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Oxidative Stress1 pathway

▸▣ Lead-induced Oxidative Stress Signaling

◈ TargetROS

◆CAT,SOD, GPx,and GR

▸✣ Inflammation1 pathway

▸▣ MAPK Signaling

◈ Targetp65

◆COX-2, iNOS, TNF-α and IL-1β

❀

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ NF-κB Signaling

◈ TargetIκBα

◆IL-4, IL-5, IL-13

▸✣ Oxidative Stress1 pathway

▸▣ AMPK/Nrf2/HO-1 Signaling

◈ Targetp-AMPK

◆ROS, HO-1

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ NF-κB Signaling

◈ TargetNF-κB

◆TNF-α, IL-6 and IL-1β

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Thermogenesis1 pathway

▸▣ TRPV1/β-AR Signaling

◈ TargetTRPV1

◆UCP1

⌬

Compound · 2 disease(s) · 3 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Apoptosis1 pathway

▸▣ Caspase Signaling

◈ TargetCaspase-3

◆Bcl-XL, Cleaved-Caspase-3

❀

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ TLR4/MyD88/NF-κB Signaling

◈ TargetIκBα

◆Collagen, E-cadherin, ß-catenin

▸✣ Tissue Remodelling1 pathway

▸▣ Wnt/β-catenin Signaling

◈ Targetβ-catenin

◆Collagen, E-cadherin, ß-catenin

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ NLRP3 Signaling

◈ TargetNLRP3

◆IL-1β, Caspase-1, NLRP3

⌬

Compound · 1 disease(s) · 3 pathway(s)

▸

❀

Disease · 1 process(es) · 3 pathway(s)

▸

▸✣ Inflammation3 pathways

▸▣ MAPK Signaling

◈ TargetTAK1

◆TNF-α-, IL-1β-, and IL-17

▸▣ NF-κB Signaling

◈ TargetTAK1

◆TNF-α-, IL-1β-, and IL-17

▸▣ PI3K/AKT Signaling

◈ TargetTAK1

◆TNF-α-, IL-1β-, and IL-17

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Cartilage Degeneration1 pathway

▸▣ Nrf2 Signaling

◈ TargetNrf2

◆CAT, ROS, GSH