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Thymoquinone
Compound · in 2 ingredients · 5 conditions
Thymoquinone is tracked across every ingredient that carries it and mapped to the disease biology it modulates, resolving down to molecular targets and biomarkers with linked evidence.
Found in these ingredients
Comparison
Compound → Diseases → Biological Processes → Pathways → Biomarkers
All
Disease
Biological Process
Molecular Pathway
Disease · 6 process(es) · 6 pathway(s)▸
Disease · 6 process(es) · 6 pathway(s)
▸✣ Inflammation1 pathway
▸▣ TNF-α/TNFR Signaling
◆TNF-α, IL-6, IL-1β
▸✣ Epithelial-Mesenchymal Transition1 pathway
▸▣ ERK/HIF-1α Signaling
◆E-cadherin, N-cadherin, Vimentin
▸✣ Oxidative Stress1 pathway
▸▣ Nrf2/ARE Signaling
◆CAT, SOD, GPX
▸✣ Apoptosis1 pathway
▸▣ NF-κB Signaling
◆Caspase-3, Caspase-9, PARP, BCL-2, BAX
▸✣ Cell Proliferation1 pathway
▸▣ PI3K/AKT Signaling
◆BCL-2 and BCL-xL
▸✣ Ovarian Steroidogenesis1 pathway
▸▣ CYP17A1/CYP19A1 Modulation
◆E1/E2 ratio, AS, TT
Disease · 1 process(es) · 4 pathway(s)▸
Disease · 1 process(es) · 4 pathway(s)
▸✣ Inflammation4 pathways
▸▣ NF-κB Signaling
◆COX-2, PGE2, 5-LOX
▸▣ Innate immune Signaling
◆IFN-γ
▸▣ TNF-α/ASK1/MAPK Signaling
◆ICAM-1, VCAM-1, Cad-11
▸▣ IL-1β Signaling
◆NO, PGE2, MMP-1, MMP-3, and MMP-13
Disease · 1 process(es) · 2 pathway(s)▸
Disease · 1 process(es) · 2 pathway(s)
▸✣ Inflammation2 pathways
▸▣ TPA-induced COX-2 Signaling
◆COX-2
▸▣ NLRP3 Signaling
◆IL-1β, IL-18
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Neurodegeneration1 pathway
▸▣ ROS Signaling
◆BCL-2, ROS
Disease · 1 process(es) · 1 pathway(s)▸
Disease · 1 process(es) · 1 pathway(s)
▸✣ Inflammation1 pathway
▸▣ Inflammatory Signaling
◆Histamine/serotonin