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Cardiovascular Diseases
Disease Page: NO01
Cardiovascular disease (CVD) is a broad term for conditions that affect the heart and blood vessels, acting as the leading cause of death worldwide. It generally develops through atherosclerosis, a process where fatty deposits and cholesterol build up inside the arteries. Over time, this plaque causes the arteries to narrow and stiffen, severely restricting healthy blood flow throughout the body. When a plaque rupture or a blood clot completely blocks these channels, it can trigger critical, life-threatening medical emergencies, most notably heart attacks or strokes
Biological Processes of Cardiovascular Diseases
Explore the key biological processes that drive cardiovascular diseases, from cellular mechanisms through tissue-level responses.
✣NO Production2 pathway(s)▸
NO Production
2 pathway(s)
▣eNOS/KLF2 PathwayTarget: eNOS/KLF2 Pathway▸
eNOS/KLF2 Pathway
Target: eNOS/KLF2 Pathway
eNOS protein
KLF2
▣NO PathwayTarget: NO Pathway▸
NO Pathway
Target: NO Pathway
NO
✣Calcium Influx2 pathway(s)▸
Calcium Influx
2 pathway(s)
▣PI3K PathwayTarget: PI3K Pathway▸
PI3K Pathway
Target: PI3K Pathway
PI3K
▣IP3 PathwayTarget: IP3 Pathway▸
IP3 Pathway
Target: IP3 Pathway
Ca_c
IP3