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Piperlongumine
Compound · in 1 ingredients · 4 conditions

Piperlongumine is tracked across every ingredient that carries it and mapped to the disease biology it modulates, resolving down to molecular targets and biomarkers with linked evidence.

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Comparison

All Disease Biological Process Molecular Pathway
Disease · 2 process(es) · 2 pathway(s)
Apoptosis1 pathway
AKT Signaling
◈ TargetROS♧ IngredientLong Pepper
Bcl-xL
Inflammation1 pathway
NF-κB Signaling
◈ TargetTNF-α♧ IngredientLong Pepper
IL-6, IL-8, MMP-9, ICAM-1
Disease · 1 process(es) · 1 pathway(s)
Apoptosis1 pathway
RO-induced Apoptotic Signaling
◈ TargetROS♧ IngredientLong Pepper
Caspase-3
Disease · 2 process(es) · 2 pathway(s)
Cell Cycle Progression1 pathway
JAK/STAT3 Signaling
◈ Targetp-JAK1/2♧ IngredientLong Pepper
Cycin D
Cell Cycle Invasion1 pathway
JAK/STAT3 Signaling
◈ Targetp-JAK1/2♧ IngredientLong Pepper
MMP-9, TWIST
Disease · 1 process(es) · 1 pathway(s)
Osteoclastogenesis1 pathway
RANKL Signaling
◈ TargetNF-κB♧ IngredientLong Pepper
TNFα, IL-1β, IL-6, PGE-2