phyllanthus-niruri - Gods

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Phyllanthus niruri

Ingredient · 6 compounds · 1 conditions

Phyllanthus niruri is profiled across the CytoSolve® knowledge base and mapped to the disease biology it influences — tracing each of its compounds through disease, biological process, molecular pathway and down to individual biomarkers, with source videos and references at each step.

Compounds in this ingredient

⌬Astragalin ⌬Corilagin ⌬Geraniin ⌬Hypophyllanthin ⌬Niranthin ⌬Rutin

Conditions addressed

❀Bowel Health

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Ingredient → Compounds → Diseases → Biological Processes → Molecular Pathways → Biomarkers

All Compound Disease Biological Process Molecular Pathway

⌬

Compound · 1 disease(s) · 3 pathway(s)

▸

❀

Disease · 2 process(es) · 3 pathway(s)

▸

▸✣ Apoptosis2 pathways

▸▣ ROS-induced Apoptosis Signaling

◈ TargetROS

◆ROS, Caspase -8, -9, -3 and PARP

▸▣ ROS Signaling

◈ TargetROS

◆ROS, Caspase -8, -9, -3 and PARP

▸✣ Autophagy1 pathway

▸▣ AMPK/Sirt1 Signaling

◈ Targetp-AMPK

◆MDA, GSH, MPO

⌬

Compound · 1 disease(s) · 2 pathway(s)

▸

❀

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Intestinal Barrier Dysfunction1 pathway

▸▣ IL-1β Signaling

◈ TargetIL-1β

◆Claudin, Occludin, ZO-1

▸✣ Inflammation1 pathway

▸▣ LPS/NF-κB Signaling

◈ TargetNF-κB

◆NO, iNOS

⌬

Compound · 1 disease(s) · 3 pathway(s)

▸

❀

Disease · 3 process(es) · 3 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ LPS/NF-κB Signaling

◈ TargetNF-κB

◆IL-6, IL-1β, and TNF-α

▸✣ Intestinal Barrier Dysfunction1 pathway

▸▣ LPS/NF-κB Signaling

◈ TargetNF-κB

◆ZO-1 and Claudin-1

▸✣ Intestinal Mucosal Dysfunction1 pathway

▸▣ LPS/NF-κB Signaling

◈ TargetNF-κB

◆MUC2

⌬

Hypophyllanthin

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ LPS/TLR4 Signaling

◈ TargetTLR4

◆IL-1β, TNF-α, COX-2, PGE-2

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ LPS/TLR4 Signaling

◈ TargetTLR4

◆IL-1β, TNF-α, COX-2, PGE-2

⌬

Compound · 1 disease(s) · 2 pathway(s)

▸

❀

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Oxidative Stress1 pathway

▸▣ ROS Signaling

◈ TargetROS

◆MDA, ROS

▸✣ Inflammation1 pathway

▸▣ Stress Hormone-induced Inflammatory Signaling

◈ TargetNF-κB

◆TNF-α, IL-6, COX-2, iNOS