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Ajwain
Ingredient · 6 compounds · 2 conditions

Ajwain is profiled across the CytoSolve® knowledge base and mapped to the disease biology it influences — tracing each of its compounds through disease, biological process, molecular pathway and down to individual biomarkers, with source videos and references at each step.

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Comparison

All Compound Disease Biological Process Molecular Pathway
Compound · 2 disease(s) · 3 pathway(s)
Disease · 1 process(es) · 2 pathway(s)
Inflammation2 pathways
NF-κB Signaling
◈ TargetIκB
COX-2, NO
◈ TargetTLR4
TNF-α, IL-1β
MAPK Signaling
◈ Targetp-p38 MAPK
NO, IL-6
◈ Targetp-ERK
TNF-α
◈ Targetp-JNK
COX-2
Disease · 1 process(es) · 1 pathway(s)
Inflammation1 pathway
NLRP3 Signaling
◈ TargetNLRP3
5-HT, NE, IL-1β, IL-6,TNF-α, NLRP3, ASC, caspase-1
Compound · 2 disease(s) · 3 pathway(s)
Disease · 1 process(es) · 2 pathway(s)
Inflammation2 pathways
NF-κB Signaling
◈ TargetIκB
TNF-α, IL-1β, IL-6
MAPK Signaling
◈ Targetp-p38 MAPK
TNF-α
◈ Targetp-ERK
IL-1β
◈ Targetp-JNK
IL-6
Disease · 1 process(es) · 1 pathway(s)
Lipid Peroxidation1 pathway
Oxidative Stress Signaling
◈ TargetROS
NO, SOD, CAT
Compound · 2 disease(s) · 3 pathway(s)
Disease · 1 process(es) · 1 pathway(s)
Inflammation1 pathway
NF-κB Signaling
◈ TargetIκB
IL-1β, TNF-α, IL-6, PGE2, IL-10
Disease · 1 process(es) · 2 pathway(s)
Nociception2 pathways
Cholinergic Signaling
◈ TargetCholinergic System
Naloxone, Atropine
Opioid Signaling
◈ TargetOpioid System
Naloxone, Atropine
Compound · 1 disease(s) · 2 pathway(s)
Disease · 2 process(es) · 2 pathway(s)
Neuroinflammation1 pathway
NF-κB Signaling
◈ TargetCOX-2◈ TargetERK1/2
TNF-α, IL-1β, IL-6, TGF-β, IL-10
Apoptosis1 pathway
Intrinstic Mitochondrial Pathway
◈ TargetCaspase-3
BCL-2, BAX, Cytochrome-c
Compound · 1 disease(s) · 1 pathway(s)
Disease · 1 process(es) · 1 pathway(s)
NREMS1 pathway
GABAA/BZD Signaling
◈ TargetGABAA-Benzodiazepine receptor
Flumazenil
Compound · 1 disease(s) · 1 pathway(s)
Disease · 1 process(es) · 1 pathway(s)
Anxiety1 pathway
Adenosine A2a Signaling
◈ TargetAdenosine A2a receptor◈ TargetAChE
Tyrosine Hydroxylase, GAD-67, GFAP & IBA-1