pet-skin-health

Pet Skin Health - Gods
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Pet Skin Health

Disease / Phenomenon

The skin and coat wellness of companion animals — supporting the barrier, immune balance, and resilience that keep an animal's skin healthy and comfortable.

Biological Processes of Pet Skin Health

Explore the key biological processes that drive pet skin health, from cellular mechanisms through tissue-level responses.

✣
Detoxification
1 pathway(s)
▸
▣
Intestinal Nitrogen Metabolism
Target: Ammonium
▸
Renal Ammonium Excretion
♧ Ingredient: Zeolite ⌬ Compound: Zeolite
▶ Video
✣
Dyslipidemia
1 pathway(s)
▸
▣
LXRα/β–ABCG5/G8 Signaling
Target: LXRα/β
▸
LXRα and LXRβ mRNA
♧ Ingredient: Diatomaceous Earth ⌬ Compound: Diatomaceous Earth
▶ Video
✣
Inflammation
8 pathway(s)
▸
▣
COX-mediated Signaling
Target: COX-2
▸
PGE2
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
IL-6
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
TNF-α
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
▣
Arachidonic Acid Signaling
Target: PGE1
▸
PGE1
♧ Ingredient: Spirulina ⌬ Compound: γ-Linolenic Acid
▶ Video
▣
LPS/TLR4 Signaling
Target: NF‐κB
▸
IL‐33
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
IL 1β
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
IL‐6
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
and IL‐8
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
▣
Carbohydrate Metabolism Signaling
Target: Parasutterella Proliferation
▸
Succinic Acid
♧ Ingredient: Spirulina ⌬ Compound: Gallic Acid
▶ Video
▣
TLR-mediated Signaling
Target: TLR 8
▸
IL-6
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
IL-8
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
IL-10
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
TNF-α
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
▣
NF-κB/MAPK Signaling
Target: ERK
▸
IL-1β
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Rutin
▶ Video
IL-6
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Rutin
▶ Video
TNF-α.
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Rutin
▶ Video
▣
TLR/NF-κB Signaling
Target: Lipoxygenase-2
▸
TNF-α
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
IL-2
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
IL-6
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
▣
NF-κB Signaling
Target: IκB
▸
TNF-α
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
IL-8
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
COX-2
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
✣
Chondral Degeneration
1 pathway(s)
▸
▣
MMP Signaling
Target: MMP-3
▸
sGAGs
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
MMP-3
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
✣
Vascular Relaxation
1 pathway(s)
▸
▣
NO/eNOS Signaling
Target: eNOS
▸
NO
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
✣
Reproductive
1 pathway(s)
▸
▣
Δ-5 Desaturase Signaling
Target: Δ-5 Desaturase
▸
GLA
♧ Ingredient: Spirulina ⌬ Compound: γ-Linolenic Acid
▶ Video
DGLA
♧ Ingredient: Spirulina ⌬ Compound: γ-Linolenic Acid
▶ Video
ARA
♧ Ingredient: Spirulina ⌬ Compound: γ-Linolenic Acid
▶ Video
✣
Immunomodulation
1 pathway(s)
▸
▣
Humoral Immune Signaling
Target: CD4+ T cells
▸
CD4+
♧ Ingredient: Spirulina ⌬ Compound: β-Carotene
▶ Video
CD4:CD8
♧ Ingredient: Spirulina ⌬ Compound: β-Carotene
▶ Video
✣
Apoptosis
3 pathway(s)
▸
▣
Caspase Signaling
Target: Caspase-8
▸
Annexin V
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
ß actin
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
▣
PI3K/AKT Signaling
Target: p‐AKT
▸
BAX
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Quercetin
▶ Video
BCL-2
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Quercetin
▶ Video
▣
Caspase-3 Signaling
Target: Caspase-3
▸
Bax/Bcl-2 ratio
♧ Ingredient: Fenugreek ⌬ Compound: Esculetin
▶ Video
✣
Angiogenesis
1 pathway(s)
▸
▣
VEGF-A/VEGFR-2 Signaling
Target: Ang2
▸
VE-cadherin
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
VEGF-A
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
VEGFR-2
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
GAPDH
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
✣
Oxidative Stress
3 pathway(s)
▸
▣
Nrf2 Signaling
Target: Keap1
▸
SOD1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ellagic Acid
▶ Video
SOD2
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ellagic Acid
▶ Video
▣
JNK/Nrf2 Signaling
Target: p-JNK
▸
HO-1
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Hyperoside
▶ Video
ROS
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Hyperoside
▶ Video
MDA
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Hyperoside
▶ Video
▣
Oxidative Stress Signaling
Target: ROS
▸
ROS
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
✣
Thyroxine Hormone Regulation
1 pathway(s)
▸
▣
Sodium Iodide Symporter Signaling
Target: Thryoid folicular cells,Pendrin
▸
Thyroid Hormone
♧ Ingredient: Kelp ⌬ Compound: Iodine
▶ Video
✣
Antioxidant
2 pathway(s)
▸
▣
Oxidative Stress Signaling
Target: ROS
▸
ROS
♧ Ingredient: Kelp ⌬ Compound: Fucoidan
▶ Video
▣
Lipid peroxidation
Target: ROS
▸
MDA
♧ Ingredient: Turmeric ⌬ Compound: Hyaluronic Acid
▶ Video
✣
Viral Replication
1 pathway(s)
▸
▣
Nrf2 Signaling
Target: Nrf2
▸
SOD
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Rutin
▶ Video
HO-1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Rutin
▶ Video
NQO1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Rutin
▶ Video
✣
Cell Proliferation
2 pathway(s)
▸
▣
MAPK Signaling
Target: p-p38
▸
Cleaved Caspase‐3
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Quercetin
▶ Video
▣
Cell Cycle Signaling
Target: CDK4/cyclin D1
▸
CDK4
♧ Ingredient: Fenugreek ⌬ Compound: Esculetin
▶ Video
Cyclin D1
♧ Ingredient: Fenugreek ⌬ Compound: Esculetin
▶ Video
✣
Muscle Regeneration
1 pathway(s)
▸
▣
PDK1 Signaling
Target: PDK1
▸
PDK1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ferulic Acid
▶ Video
miR-6529
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ferulic Acid
▶ Video
✣
Muscle Atrophy
1 pathway(s)
▸
▣
FOXO Signaling
Target: MuRF1
▸
MuRF1
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Ursolic Acid
▶ Video
✣
Lipid Peroxidation
1 pathway(s)
▸
▣
Antioxidant Signaling
Target: ROS
▸
SOD
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
CAT
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
GSH-Px
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
GST
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
and GSH
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
✣
Autophagy
1 pathway(s)
▸
▣
Autophagy Signaling
Target: LC3-II
▸
LC3
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
ULK1
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
Atg7
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
and Atg12
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
✣
Cartilage Degeneration
1 pathway(s)
▸
▣
IL-1β Signaling
Target: NF‐κB
▸
COX-2
♧ Ingredient: Turmeric ⌬ Compound: Turmerosaccharides
▶ Video
PGE 2
♧ Ingredient: Turmeric ⌬ Compound: Turmerosaccharides
▶ Video
MMP-3
♧ Ingredient: Turmeric ⌬ Compound: Turmerosaccharides
▶ Video
✣
Insulin Resistance
1 pathway(s)
▸
▣
AHSG/TLR4 Signaling
Target: AHSG (Fetuin-A)
▸
A2HS levels
♧ Ingredient: Turmeric ⌬ Compound: Curcuminoid
▶ Video
glucose tolerance
♧ Ingredient: Turmeric ⌬ Compound: Curcuminoid
▶ Video
✣
Chondroprotective
1 pathway(s)
▸
▣
MMP Signaling
Target: MMP-13
▸
Pro-Hyp
♧ Ingredient: Turmeric ⌬ Compound: Hyaluronic Acid
▶ Video
CS
♧ Ingredient: Turmeric ⌬ Compound: Hyaluronic Acid
▶ Video

Compounds affecting Pet Skin Health

Browse active compounds and their direct impact on pet skin health biological processes, pathways, and biomarkers.

⌬
▸
✣
Inflammation
NF-κB Signaling
▸
TNF-α
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
IL-8
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
COX-2
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
✣
Autophagy
Autophagy Signaling
▸
LC3
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
ULK1
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
Atg7
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
and Atg12
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
⌬
▸
✣
Insulin Resistance
AHSG/TLR4 Signaling
▸
A2HS levels
♧ Ingredient: Turmeric ⌬ Compound: Curcuminoid
▶ Video
glucose tolerance
♧ Ingredient: Turmeric ⌬ Compound: Curcuminoid
▶ Video
⌬
▸
✣
Dyslipidemia
LXRα/β–ABCG5/G8 Signaling
▸
LXRα and LXRβ mRNA
♧ Ingredient: Diatomaceous Earth ⌬ Compound: Diatomaceous Earth
▶ Video
⌬
▸
✣
Oxidative Stress
Nrf2 Signaling
▸
SOD1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ellagic Acid
▶ Video
SOD2
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ellagic Acid
▶ Video
⌬
▸
✣
Apoptosis
Caspase-3 Signaling
▸
Bax/Bcl-2 ratio
♧ Ingredient: Fenugreek ⌬ Compound: Esculetin
▶ Video
✣
Cell Proliferation
Cell Cycle Signaling
▸
CDK4
♧ Ingredient: Fenugreek ⌬ Compound: Esculetin
▶ Video
Cyclin D1
♧ Ingredient: Fenugreek ⌬ Compound: Esculetin
▶ Video
⌬
▸
✣
Muscle Regeneration
PDK1 Signaling
▸
PDK1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ferulic Acid
▶ Video
miR-6529
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ferulic Acid
▶ Video
⌬
Fucoidan
From Kelp
▸
✣
Antioxidant
Oxidative Stress Signaling
▸
ROS
♧ Ingredient: Kelp ⌬ Compound: Fucoidan
▶ Video
⌬
▸
✣
Apoptosis
Caspase Signaling
▸
Annexin V
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
ß actin
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
✣
Angiogenesis
VEGF-A/VEGFR-2 Signaling
▸
VE-cadherin
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
VEGF-A
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
VEGFR-2
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
GAPDH
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
⌬
▸
✣
Inflammation
Carbohydrate Metabolism Signaling
▸
Succinic Acid
♧ Ingredient: Spirulina ⌬ Compound: Gallic Acid
▶ Video
✣
Lipid Peroxidation
Antioxidant Signaling
▸
SOD
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
CAT
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
GSH-Px
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
GST
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
and GSH
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
⌬
▸
✣
Antioxidant
Lipid peroxidation
▸
MDA
♧ Ingredient: Turmeric ⌬ Compound: Hyaluronic Acid
▶ Video
✣
Chondroprotective
MMP Signaling
▸
Pro-Hyp
♧ Ingredient: Turmeric ⌬ Compound: Hyaluronic Acid
▶ Video
CS
♧ Ingredient: Turmeric ⌬ Compound: Hyaluronic Acid
▶ Video
⌬
▸
✣
Oxidative Stress
JNK/Nrf2 Signaling
▸
HO-1
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Hyperoside
▶ Video
ROS
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Hyperoside
▶ Video
MDA
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Hyperoside
▶ Video
⌬
Iodine
From Kelp
▸
✣
Thyroxine Hormone Regulation
Sodium Iodide Symporter Signaling
▸
Thyroid Hormone
♧ Ingredient: Kelp ⌬ Compound: Iodine
▶ Video
⌬
▸
✣
Inflammation
LPS/TLR4 Signaling
▸
IL‐33
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
IL 1β
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
IL‐6
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
and IL‐8
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
⌬
MSM
From Horsetail
▸
✣
Inflammation
TLR-mediated Signaling
▸
IL-6
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
IL-8
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
IL-10
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
TNF-α
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
⌬
▸
✣
Inflammation
COX-mediated Signaling
▸
PGE2
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
IL-6
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
TNF-α
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
✣
Chondral Degeneration
MMP Signaling
▸
sGAGs
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
MMP-3
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
✣
Vascular Relaxation
NO/eNOS Signaling
▸
NO
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
⌬
▸
✣
Inflammation
TLR/NF-κB Signaling
▸
TNF-α
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
IL-2
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
IL-6
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
✣
Apoptosis
PI3K/AKT Signaling
▸
BAX
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Quercetin
▶ Video
BCL-2
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Quercetin
▶ Video
✣
Oxidative Stress
Oxidative Stress Signaling
▸
ROS
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
✣
Cell Proliferation
MAPK Signaling
▸
Cleaved Caspase‐3
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Quercetin
▶ Video
⌬
▸
✣
Inflammation
NF-κB/MAPK Signaling
▸
IL-1β
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Rutin
▶ Video
IL-6
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Rutin
▶ Video
TNF-α.
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Rutin
▶ Video
✣
Viral Replication
Nrf2 Signaling
▸
SOD
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Rutin
▶ Video
HO-1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Rutin
▶ Video
NQO1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Rutin
▶ Video
⌬
▸
✣
Cartilage Degeneration
IL-1β Signaling
▸
COX-2
♧ Ingredient: Turmeric ⌬ Compound: Turmerosaccharides
▶ Video
PGE 2
♧ Ingredient: Turmeric ⌬ Compound: Turmerosaccharides
▶ Video
MMP-3
♧ Ingredient: Turmeric ⌬ Compound: Turmerosaccharides
▶ Video
⌬
▸
✣
Muscle Atrophy
FOXO Signaling
▸
MuRF1
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Ursolic Acid
▶ Video
⌬
▸
✣
Detoxification
Intestinal Nitrogen Metabolism
▸
Renal Ammonium Excretion
♧ Ingredient: Zeolite ⌬ Compound: Zeolite
▶ Video
⌬
▸
✣
Immunomodulation
Humoral Immune Signaling
▸
CD4+
♧ Ingredient: Spirulina ⌬ Compound: β-Carotene
▶ Video
CD4:CD8
♧ Ingredient: Spirulina ⌬ Compound: β-Carotene
▶ Video
⌬
▸
✣
Inflammation
Arachidonic Acid Signaling
▸
PGE1
♧ Ingredient: Spirulina ⌬ Compound: γ-Linolenic Acid
▶ Video
✣
Reproductive
Δ-5 Desaturase Signaling
▸
GLA
♧ Ingredient: Spirulina ⌬ Compound: γ-Linolenic Acid
▶ Video
DGLA
♧ Ingredient: Spirulina ⌬ Compound: γ-Linolenic Acid
▶ Video
ARA
♧ Ingredient: Spirulina ⌬ Compound: γ-Linolenic Acid
▶ Video

Ingredients affecting Pet Skin Health

Explore therapeutic ingredients and their constituent compounds that modulate pet skin health biology.

♧
Diatomaceous Earth
1 active compound(s)
▸
⌬
Diatomaceous Earth
Dyslipidemia → LXRα/β–ABCG5/G8 Signaling
▸
LXRα and LXRβ mRNA
♧ Ingredient: Diatomaceous Earth ⌬ Compound: Diatomaceous Earth
▶ Video
♧
Fenugreek
1 active compound(s)
▸
⌬
Esculetin
Apoptosis → Caspase-3 Signaling
▸
Bax/Bcl-2 ratio
♧ Ingredient: Fenugreek ⌬ Compound: Esculetin
▶ Video
♧
Hawthorn Leaf and Flower
5 active compound(s)
▸
⌬
Rutin
Inflammation → NF-κB/MAPK Signaling
▸
IL-1β
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Rutin
▶ Video
IL-6
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Rutin
▶ Video
TNF-α.
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Rutin
▶ Video
⌬
Quercetin
Inflammation → TLR/NF-κB Signaling
▸
TNF-α
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
IL-2
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
IL-6
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Quercetin
▶ Video
⌬
Hyperoside
Oxidative Stress → JNK/Nrf2 Signaling
▸
HO-1
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Hyperoside
▶ Video
ROS
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Hyperoside
▶ Video
MDA
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Hyperoside
▶ Video
⌬
Ursolic Acid
Muscle Atrophy → FOXO Signaling
▸
MuRF1
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Ursolic Acid
▶ Video
⌬
Gallic Acid
Lipid Peroxidation → Antioxidant Signaling
▸
SOD
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
CAT
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
GSH-Px
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
GST
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
and GSH
♧ Ingredient: Hawthorn Leaf and Flower ⌬ Compound: Gallic Acid
▶ Video
♧
Horsetail
1 active compound(s)
▸
⌬
MSM
Inflammation → TLR-mediated Signaling
▸
IL-6
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
IL-8
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
IL-10
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
TNF-α
♧ Ingredient: Horsetail ⌬ Compound: MSM
▶ Video
♧
Kelp
3 active compound(s)
▸
⌬
Fucoxanthin
Apoptosis → Caspase Signaling
▸
Annexin V
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
ß actin
♧ Ingredient: Kelp ⌬ Compound: Fucoxanthin
▶ Video
⌬
Iodine
Thyroxine Hormone Regulation → Sodium Iodide Symporter Signaling
▸
Thyroid Hormone
♧ Ingredient: Kelp ⌬ Compound: Iodine
▶ Video
⌬
Fucoidan
Antioxidant → Oxidative Stress Signaling
▸
ROS
♧ Ingredient: Kelp ⌬ Compound: Fucoidan
▶ Video
♧
Red Raspberry Leaf
4 active compound(s)
▸
⌬
Quercetin
Apoptosis → PI3K/AKT Signaling
▸
BAX
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Quercetin
▶ Video
BCL-2
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Quercetin
▶ Video
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Ellagic Acid
Oxidative Stress → Nrf2 Signaling
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SOD1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ellagic Acid
▶ Video
SOD2
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ellagic Acid
▶ Video
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Rutin
Viral Replication → Nrf2 Signaling
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SOD
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Rutin
▶ Video
HO-1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Rutin
▶ Video
NQO1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Rutin
▶ Video
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Ferulic Acid
Muscle Regeneration → PDK1 Signaling
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PDK1
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ferulic Acid
▶ Video
miR-6529
♧ Ingredient: Red Raspberry Leaf ⌬ Compound: Ferulic Acid
▶ Video
♧
Spirulina
5 active compound(s)
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⌬
Phycocyanin
Inflammation → COX-mediated Signaling
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PGE2
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
IL-6
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
TNF-α
♧ Ingredient: Spirulina ⌬ Compound: Phycocyanin
▶ Video
⌬
γ-Linolenic Acid
Inflammation → Arachidonic Acid Signaling
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PGE1
♧ Ingredient: Spirulina ⌬ Compound: γ-Linolenic Acid
▶ Video
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Luteolin
Inflammation → LPS/TLR4 Signaling
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IL‐33
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
IL 1β
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
IL‐6
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
and IL‐8
♧ Ingredient: Spirulina ⌬ Compound: Luteolin
▶ Video
⌬
Gallic Acid
Inflammation → Carbohydrate Metabolism Signaling
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Succinic Acid
♧ Ingredient: Spirulina ⌬ Compound: Gallic Acid
▶ Video
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β-Carotene
Immunomodulation → Humoral Immune Signaling
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CD4+
♧ Ingredient: Spirulina ⌬ Compound: β-Carotene
▶ Video
CD4:CD8
♧ Ingredient: Spirulina ⌬ Compound: β-Carotene
▶ Video
♧
Turmeric
4 active compound(s)
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⌬
Curcumin
Inflammation → NF-κB Signaling
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TNF-α
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
IL-8
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
COX-2
♧ Ingredient: Turmeric ⌬ Compound: Curcumin
▶ Video
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Hyaluronic Acid
Antioxidant → Lipid peroxidation
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MDA
♧ Ingredient: Turmeric ⌬ Compound: Hyaluronic Acid
▶ Video
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Turmerosaccharides
Cartilage Degeneration → IL-1β Signaling
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COX-2
♧ Ingredient: Turmeric ⌬ Compound: Turmerosaccharides
▶ Video
PGE 2
♧ Ingredient: Turmeric ⌬ Compound: Turmerosaccharides
▶ Video
MMP-3
♧ Ingredient: Turmeric ⌬ Compound: Turmerosaccharides
▶ Video
⌬
Curcuminoid
Insulin Resistance → AHSG/TLR4 Signaling
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A2HS levels
♧ Ingredient: Turmeric ⌬ Compound: Curcuminoid
▶ Video
glucose tolerance
♧ Ingredient: Turmeric ⌬ Compound: Curcuminoid
▶ Video
♧
Zeolite
1 active compound(s)
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⌬
Zeolite
Detoxification → Intestinal Nitrogen Metabolism
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Renal Ammonium Excretion
♧ Ingredient: Zeolite ⌬ Compound: Zeolite
▶ Video