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Turmeric

Ingredient · 7 compounds · 10 conditions

Turmeric is profiled across the CytoSolve® knowledge base and mapped to the disease biology it influences — tracing each of its compounds through disease, biological process, molecular pathway and down to individual biomarkers, with source videos and references at each step.

Compounds in this ingredient

⌬Curcumin ⌬Curcuminoid ⌬Ferulic Acid ⌬Hyaluronic Acid ⌬Limonene ⌬Quercetin ⌬Turmerosaccharides

Conditions addressed

❀Alzheimer's Disease ❀Asthma ❀Bowel Health ❀Eye Health ❀Gut-Brain Health ❀Men's Health ❀Pet Skin Health ❀Skin Diseases ❀Viral Infections ❀Women's Health

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Ingredient → Compounds → Diseases → Biological Processes → Molecular Pathways → Biomarkers

All Compound Disease Biological Process Molecular Pathway

⌬

Compound · 8 disease(s) · 20 pathway(s)

▸

❀

Alzheimer's Disease

Disease · 3 process(es) · 3 pathway(s)

▸

▸✣ Oxidative Stress1 pathway

▸▣ ROS Signaling

◈ TargetROS

◆ROS

▸✣ Neurodegeneration1 pathway

▸▣ ROS Signaling

◈ TargetAß aggregation

◆MDA, BAX/BCL-2 Ratio, 8-OHdG, and 8 OHG

▸✣ NeuroInflammation1 pathway

▸▣ NF-κB Signaling

◈ TargetNF-κB

◆PGE2, NO, and TNF-α

❀

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Cell cycle progression1 pathway

▸▣ p53/p21 Signaling

◈ Targetp53

◆CDK2, cyclin A, p53, p21

▸✣ Inflammation1 pathway

▸▣ NF-κB Signaling

◈ TargetNF-κB

◆TNF-α, IL-1, IL-6

❀

Disease · 2 process(es) · 3 pathway(s)

▸

▸✣ Inflammation2 pathways

▸▣ p38 MAPK Signaling

◈ TargetNF-κB

◆IL-1β

▸▣ IL-1β Signaling

◈ TargetNF-κB

◆Occludin, ZO-1

▸✣ Diabetic Cataract1 pathway

▸▣ ROS/αB Crystallin aggregation Signaling

◈ TargetROS

◆ROS, αB Crystals

❀

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ TNFR/NF-κB Signaling

◈ TargetNF-κB

◆TNF-α, IL-6, IL-8

▸✣ Melanogenesis1 pathway

▸▣ ERK/MITF Signaling

◈ TargetERK

◆Microphthalmia‐associated transcription factor (MITF), tyrosine, tyrosinase‐related protein 1 and 2 (TRP-1 and TRP-2) expression

❀

Disease · 3 process(es) · 3 pathway(s)

▸

▸✣ Hyperandrogenism1 pathway

▸▣ Hormone-induced Hyperandrogenism Signaling

◈ TargetProgesterone and FSH

◆FSH, Progesterone, Testosterone, LH, Estradiol

▸✣ Inflammation1 pathway

▸▣ NF-κB Signaling

◈ TargetNF-κB

◆COX-2, PGE-2

▸✣ Cell Proliferation1 pathway

▸▣ EGFR Signaling

◈ TargetGSK-3β

◆AKT, GSK3β, and HER2

❀

Viral Infections

Disease · 1 process(es) · 3 pathway(s)

▸

▸✣ Inflammation3 pathways

▸▣ Th2/Th17 Signaling

◈ TargetIL-2

◆IL-2

▸▣ M1 Polarization Signaling

◈ TargetROS

◆ROS

▸▣ NF-κB Signaling

◈ TargetNF-κB

◆TNF-α, IL-6, IL-1β, and IL-2

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ TNF-α/NF-κB Signaling

◈ TargetTNF-α

◆IL-6, IL-2, IL-5, GM-CSF

❀

Pet Skin Health

Disease · 3 process(es) · 3 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ NF-κB Signaling

◈ TargetIκB

◆TNF-α, IL-8, COX-2

▸✣ Autophagy1 pathway

▸▣ Autophagy Signaling

◈ TargetLC3-II

◆LC3, ULK1, Atg7, and Atg12

▸✣ Cartilage Degeneration1 pathway

▸▣ IL-1β Signaling

◈ Targetp-p65

◆COX-2, PGE 2, MMP-3

⌬

Compound · 5 disease(s) · 6 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Mucus Hypersecretion1 pathway

▸▣ PKC/EGFR/ERK Signaling

◈ TargetPKC

◆PKC, Mucin-5

❀

Viral Infections

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ JAK/STAT3 Signaling

◈ TargetJAK1

◆IL-6

❀

Gut-Brain Health

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Oxidative Stress1 pathway

▸▣ ROS Signaling

◈ TargetROS

◆ROS

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Testosterone Degradation1 pathway

▸▣ Testosterone Degradation Signaling

◈ TargetAromatase

◆Aromatase

❀

Pet Skin Health

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Apoptosis1 pathway

▸▣ PI3K/AKT Signaling

◈ Targetp‐AKT

◆Cleaved Caspase‐3

▸✣ Cell Proliferation1 pathway

▸▣ MAPK Signaling

◈ Targetp-p38

◆Cleaved Caspase‐3

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Inflammation1 pathway

▸▣ cAMP/PKA Signaling

◈ TargetA2A receptor

◆IgG, IgE, IL-5

⌬

Turmerosaccharides

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Pet Skin Health

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Cartilage Degeneration1 pathway

▸▣ IL-1β Signaling

◈ TargetNF‐κB

◆IL-6, IL- 8, COX-2, PGE2, TNF-α, ICAM-1

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Pet Skin Health

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Insulin Resistance1 pathway

▸▣ AHSG/TLR4 Signaling

◈ TargetAHSG (Fetuin-A)

◆A2HS levels, glucose tolerance

⌬

Compound · 1 disease(s) · 1 pathway(s)

▸

❀

Pet Skin Health

Disease · 1 process(es) · 1 pathway(s)

▸

▸✣ Muscle Regeneration1 pathway

▸▣ PDK1 Signaling

◈ TargetPDK1

◆PDK1, miR-6529

⌬

Hyaluronic Acid

Compound · 1 disease(s) · 2 pathway(s)

▸

❀

Pet Skin Health

Disease · 2 process(es) · 2 pathway(s)

▸

▸✣ Antioxidant1 pathway

▸▣ Lipid peroxidation

◈ TargetROS

◆MDA

▸✣ Chondroprotective1 pathway

▸▣ MMP Signaling

◈ TargetMMP-3◈ TargetMMP-13

◆Pro-Hyp, CS