Inflammation - Gods
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Inflammation

Disease / Phenomenon

The body's core protective response to injury or threat; helpful in short bursts, but when it lingers it can quietly damage tissues and fuel chronic disease.

Biological Processes of Inflammation

Explore the key biological processes that drive inflammation, from cellular mechanisms through tissue-level responses.

Inflammation
9 pathway(s)
NF-κB Signaling
Target: NF-κB
TNF-α and IL-1β
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
JAK/STAT Signaling
Target: STAT4
TNF-α and IL-1β
♧ Ingredient: Rosemary ⌬ Compound: Carnosol
JAK/STAT3 Signaling
Target: STAT3
IL-6
♧ Ingredient: Rhodiola ⌬ Compound: Salidroside
STAT3
♧ Ingredient: Rhodiola ⌬ Compound: Salidroside
CRH/NF-κB Signaling
Target: NF-κB
IL-6
♧ Ingredient: Rhodiola ⌬ Compound: Salidroside
LPS/TLR Signaling
Target: NF-κB
iNOS & NO
♧ Ingredient: Chamomile ⌬ Compound: Apigenin
ROS/NF-κB Signaling
Target: ROS
SOD
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
CAT
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
GPX
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
IL-1β
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
IL-6 and TNF-α
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
TNF-α/NF-κB Signaling
Target: TNF-α
TNF-α and IL-1β
♧ Ingredient: Ashwagandha ⌬ Compound: Withaferin A
IL-6 Signaling
Target: IL-6
IL-6
♧ Ingredient: Ashwagandha ⌬ Compound: Withaferin A
STAT3
♧ Ingredient: Ashwagandha ⌬ Compound: Withaferin A
FFA/TLR2/4 Signaling
Target: NF-κB
TNF-α
♧ Ingredient: Green Tea ⌬ Compound: Epicatechin
IL-1β and CCL2
♧ Ingredient: Green Tea ⌬ Compound: Epicatechin
Oxidative Stress
2 pathway(s)
Nrf2/Keap Signaling
Target: Nrf2
ROS
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
CAT
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
GST
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
CAT
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
HO-1
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
ROS Signaling
Target: ROS
ROS
♧ Ingredient: Green Tea ⌬ Compound: Epicatechin

Compounds affecting Inflammation

Browse active compounds and their direct impact on inflammation biological processes, pathways, and biomarkers.

Inflammation
LPS/TLR Signaling
iNOS & NO
♧ Ingredient: Chamomile ⌬ Compound: Apigenin
Oxidative Stress
Nrf2/Keap Signaling
ROS
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
CAT
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
GST
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
CAT
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
HO-1
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
Inflammation
JAK/STAT Signaling
TNF-α and IL-1β
♧ Ingredient: Rosemary ⌬ Compound: Carnosol
Inflammation
FFA/TLR2/4 Signaling
TNF-α
♧ Ingredient: Green Tea ⌬ Compound: Epicatechin
IL-1β and CCL2
♧ Ingredient: Green Tea ⌬ Compound: Epicatechin
Oxidative Stress
ROS Signaling
ROS
♧ Ingredient: Green Tea ⌬ Compound: Epicatechin
Inflammation
NF-κB Signaling
TNF-α and IL-1β
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
Inflammation
ROS/NF-κB Signaling
SOD
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
CAT
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
GPX
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
IL-1β
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
IL-6 and TNF-α
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
Inflammation
JAK/STAT3 Signaling
IL-6
♧ Ingredient: Rhodiola ⌬ Compound: Salidroside
STAT3
♧ Ingredient: Rhodiola ⌬ Compound: Salidroside
Inflammation
CRH/NF-κB Signaling
IL-6
♧ Ingredient: Rhodiola ⌬ Compound: Salidroside
Inflammation
TNF-α/NF-κB Signaling
TNF-α and IL-1β
♧ Ingredient: Ashwagandha ⌬ Compound: Withaferin A
Inflammation
IL-6 Signaling
IL-6
♧ Ingredient: Ashwagandha ⌬ Compound: Withaferin A
STAT3
♧ Ingredient: Ashwagandha ⌬ Compound: Withaferin A

Ingredients affecting Inflammation

Explore therapeutic ingredients and their constituent compounds that modulate inflammation biology.

0 active compound(s)
1 active compound(s)
Inflammation → TNF-α/NF-κB Signaling
TNF-α and IL-1β
♧ Ingredient: Ashwagandha ⌬ Compound: Withaferin A
1 active compound(s)
Inflammation → LPS/TLR Signaling
iNOS & NO
♧ Ingredient: Chamomile ⌬ Compound: Apigenin
0 active compound(s)
0 active compound(s)
0 active compound(s)
1 active compound(s)
Inflammation → FFA/TLR2/4 Signaling
TNF-α
♧ Ingredient: Green Tea ⌬ Compound: Epicatechin
IL-1β and CCL2
♧ Ingredient: Green Tea ⌬ Compound: Epicatechin
1 active compound(s)
Inflammation → NF-κB Signaling
TNF-α and IL-1β
♧ Ingredient: Lemon Balm ⌬ Compound: Rosmarinic acid
1 active compound(s)
Inflammation → JAK/STAT3 Signaling
IL-6
♧ Ingredient: Rhodiola ⌬ Compound: Salidroside
STAT3
♧ Ingredient: Rhodiola ⌬ Compound: Salidroside
2 active compound(s)
Inflammation → JAK/STAT Signaling
TNF-α and IL-1β
♧ Ingredient: Rosemary ⌬ Compound: Carnosol
Oxidative Stress → Nrf2/Keap Signaling
ROS
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
CAT
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
GST
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
CAT
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
HO-1
♧ Ingredient: Rosemary ⌬ Compound: Carnosic acid
0 active compound(s)