ALS Molecular Pathway ✦
ALS Pathway Page
ER stress signaling
ER stress signaling is mapped to ALS through the biological process layer Neurodegeneration. This page links the pathway to its biomarkers from the supplied ALS dataset.
✣Neurodegeneration▣Molecular Pathway◆9 Biomarkers Linked
ER Stress Signaling · Pathway Diagram
Pathway Information
ER stress signaling is a molecular pathway connected to Neurodegeneration in the ALS disease map. It consists of nine biomarkers from the workbook data.
Biomarker: BiPBiomarker: PERKBiomarker: CHOPBiomarker: XBP1Biomarker: eIF2αBiomarker: p53Biomarker: Caspase-12Biomarker: Caspase 3Biomarker: GADD34
Biomarkers · ER stress signaling
BiP
Biomarker measured within this pathway.
3D · PDB 5E84
PERK
Biomarker measured within this pathway.
3D · PDB 4G31
CHOP
Biomarker measured within this pathway.
3D · PDB 1GU5
XBP1
Biomarker measured within this pathway.
3D · PDB 1H8U
eIF2α
Biomarker measured within this pathway.
3D · PDB 1KL9
p53
Biomarker measured within this pathway.
3D · PDB 1TUP
Caspase-12
Biomarker measured within this pathway.
3D · PDB 1ICE
Caspase 3
Biomarker measured within this pathway.
3D · PDB 1CP3
GADD34
Biomarker measured within this pathway.
3D · PDB 4XPR