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Bacoside B · Compound · GODS.com
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Bacoside B

Bacoside B is one of 22 compounds indexed in the ALS scoring workbook. It is measured against the 4-tier CytoSolve hierarchy: Tier 1 disease (Amyotrophic Lateral Sclerosis) → biological processes (3) → molecular pathways (5) → Tier 4 biomarkers (7). This page surfaces every measurement field from the workbook plus the source ingredients carrying this compound.

ALS Disease Rating
9.98
Interpretation
Minimal efficacy
Test Dosage
500 mg
Biomarker
7

Diseases this compound is indexed against

Tier 1 · macro-level biological phenomena

#1
Amyotrophic Lateral Sclerosis (ALS)
Lou Gehrig's disease · 3 processes · 5 pathways · 7 biomarkers
9.98

Ingredients containing Bacoside B

Whole-food and botanical sources of this compound · 1 ingredient

◇
Bacopa Monnieri
Source of Bacoside B · inherits 9.98/100 ALS rating
9.98

Biological Processes · Pathways · Biomarkers

4-tier drill-down · click any node to expand the next tier

✣
Neuroinflammation
2 pathways
15.49
›
◇
IL-6 Signaling
2 biomarkers
30.99
›
◆ IL-6
Tier 4 biomarker — desired direction: Down
Direction: DownControl: 0.0314Healthy: 1.915e-04Effect: 0.0219Efficacy: 30.3897%BM Weight: 1Confidence: 1Weighted: 30.3897
30.39
◆ TNF-a
Tier 4 biomarker — desired direction: Down
Direction: DownControl: 18.3195Healthy: 0.221Effect: 12.6359Efficacy: 31.0244%BM Weight: 1Confidence: 1Weighted: 31.0244
31.02
◇
NLRP3 Signaling
1 biomarkers
0.00
›
◆ IL-1B
Tier 4 biomarker — desired direction: Down
Direction: DownControl: 3.6Healthy: 0.286BM Weight: 1Confidence: 1
0.00
✣
Muscle Atrophy
1 pathways
3.46
›
◇
Agrin Signaling
2 biomarkers
3.46
›
◆ MuRF1
Tier 4 biomarker — desired direction: Down
Direction: DownControl: 248.9186Healthy: 0Effect: 242Efficacy: 2.7794%BM Weight: 1Confidence: 1Weighted: 2.7794
2.78
◆ MyHC
Tier 4 biomarker — desired direction: Up
Direction: UpControl: 0.158Healthy: 0.5Effect: 0.167Efficacy: 5.6636%BM Weight: 1Confidence: 1Weighted: 5.6636
5.66
✣
Neurodegeneration / ER Stress
2 pathways
0.00
›
◇
ER Stress / Calcium Dysregulation
1 biomarkers
0.00
›
◆ Ca2+
Tier 4 biomarker — desired direction: Down
Direction: DownControl: 1.997e+06Healthy: 2.000e+05BM Weight: 1Confidence: 1
0.00
◇
FasL / Extrinsic Apoptosis
1 biomarkers
0.00
›
◆ FasL
Tier 4 biomarker — desired direction: Down
Direction: DownControl: 0.0364Healthy: 1.110e-03BM Weight: 1Confidence: 1
0.00

Biomarker measurement matrix

Every Tier 4 biomarker tracked for Bacoside B with control / healthy / effect levels

BiomarkerPathwayDirection ControlHealthyEffect Efficacy %Score (0–100)
IL-6 IL-6 Signaling Down 0.0314 1.915e-04 0.0219 30.3897 30.39
TNF-a IL-6 Signaling Down 18.3195 0.221 12.6359 31.0244 31.02
IL-1B NLRP3 Signaling Down 3.6 0.286 0.00
MuRF1 Agrin Signaling Down 248.9186 0 242 2.7794 2.78
MyHC Agrin Signaling Up 0.158 0.5 0.167 5.6636 5.66
Ca2+ ER Stress / Calcium Dysregulation Down 1.997e+06 2.000e+05 0.00
FasL FasL / Extrinsic Apoptosis Down 0.0364 1.110e-03 0.00

References

Primary literature, source data, and methodology