berberine

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Berberine
Compound · in 3 ingredients · 4 conditions

Berberine is tracked across every ingredient that carries it and mapped to the disease biology it modulates, resolving down to molecular targets and biomarkers with linked evidence.

Found in these ingredients
♧Berberis♧Heart Leaved Moon Stem♧Tree Turmeric - Stem
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Comparison

Compound → Diseases → Biological Processes → Pathways → Biomarkers
All Disease Biological Process Molecular Pathway
❀
Aging
Disease · 1 process(es) · 2 pathway(s)
▸
▸✣ Apoptosis2 pathways
▸▣ Caspase-3 Signaling
◈ TargetCytochrome C♧ IngredientBerberis
◆MMP, Caspase-9, Caspase-3
▶ Video
▸▣ Caspase Signaling
◈ TargetROS♧ IngredientBerberis
◆ROS, Ca2+, Caspase 12
▶ Video
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Diabetes
Disease · 3 process(es) · 4 pathway(s)
▸
▸✣ Oxidative Stress2 pathways
▸▣ p38/Nrf2 Signaling
◈ TargetP38♧ IngredientBerberis
◆SOD, GSH, ROS, HO-1
▶ Video
▸▣ PI3K/AKT Signaling
◈ TargetPI3K♧ IngredientBerberis
◆SOD, GSH, ROS, HO-2
▶ Video
▸✣ Inflammation1 pathway
▸▣ NF-κB Signaling
◈ TargetNF-κB♧ IngredientBerberis
◆IL-1β, IL-6, and TNF-α
▶ Video
▸✣ Insulin secretion1 pathway
▸▣ GLP-1 Signaling
◈ TargetTAS2R♧ IngredientBerberis
◆Insulin
▶ Video
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Viral Infections
Disease · 1 process(es) · 1 pathway(s)
▸
▸✣ Inflammation1 pathway
▸▣ NEK7 Signaling
◈ TargetNEK7♧ IngredientTree Turmeric - Stem
◆IL-1β
❀ Reference
❀
Osteoarthritis
Disease · 1 process(es) · 1 pathway(s)
▸
▸✣ Inflammation1 pathway
▸▣ AMPK/MPAK/NF-κB Signaling
◈ Targetp-ERK◈ Targetp-p38 MAPK◈ Targetp-JNK♧ IngredientHeart Leaved Moon Stem
◆TNF-α, IL-1β, IL-6, IL-17, IFN-γ, IL-10, TGF-β
▶ Video❀ Reference